BACKGROUND Rising maternal ages and age-related fertility decline are a global
challenge for modern reproductive medicine. Clinicians and researchers pay specific …

Aging is a complex natural process that leads to a decline in physiological functions, which
is visible in signs such as hair graying, thinning, and loss. Although hair graying is …

Progress in medicine has increased the survival time of children suffering from cancer;>
80% of patients survive for at least 5 years from the end of treatment. However, there are late …

Background Epigenetic alterations are a near-universal feature of human malignancy and
have been detected in malignant cells as well as in easily accessible specimens such as …

There is a possible accelerated biological aging in patients with substance use disorders
(SUD). The evaluation of epigenetic clocks, which are accurate estimators of biological …

Chronological age is the most important risk factor for the incidence of age-related diseases.
The pace of ageing determines the magnitude of that risk and can be expressed as …

Aberrant DNA methylation (DNAm) is known to be associated with the aetiology of cancer,
including colorectal cancer (CRC). In the past, the availability of open access data has been …

Background Compared to cancer-free persons, cancer survivors of the same chronological
age (CA) have increased physiological dysfunction, ie, higher biological age (BA), which …

Epigenetic alterations during aging are manifested with altered gene expression linking it to
lifespan regulation, genetic instability, and diseases. Diet and epigenetic modifiers exert a …

Late-onset Alzheimer's disease (LOAD) is the most common form of Alzheimer's disease
(AD) and its risk increases exponentially with aging. The incidence of LOAD is reported to …