Approaching hemophagocytic lymphohistiocytosis

A Chinnici, L Beneforti, F Pegoraro, I Trambusti… - Frontiers in …, 2023 - frontiersin.org
Hemophagocytic Lymphohistiocytosis (HLH) is a rare clinical condition characterized by
sustained but ineffective immune system activation, leading to severe and systemic …

The link between rheumatic disorders and inborn errors of immunity

G Sogkas, T Witte - EBioMedicine, 2023 - thelancet.com
Inborn errors of immunity (IEIs) are immunological disorders characterized by variable
susceptibility to infections, immune dysregulation and/or malignancies, as a consequence of …

The multifaceted immunology of cytokine storm syndrome

PY Lee, RQ Cron - The Journal of Immunology, 2023 - journals.aai.org
Cytokine storm syndromes (CSSs) are potentially fatal hyperinflammatory states that share
the underpinnings of persistent immune cell activation and uninhibited cytokine production …

Mouse models of systemic juvenile idiopathic arthritis and macrophage activation syndrome

N Inoue, GS Schulert - Arthritis Research & Therapy, 2023 - Springer
Macrophage activation syndrome (MAS) is a life-threatening complication of pediatric
rheumatic diseases, occurring most commonly in children with systemic juvenile idiopathic …

Mycobacterial immune reconstitution inflammatory syndrome in HIV is associated with protein-altering variants in hemophagocytic lymphohistiocytosis-related genes

JM Rocco, E Laidlaw, F Galindo… - The Journal of …, 2023 - academic.oup.com
People with HIV (PWH) and mycobacterial infections can develop immune reconstitution
inflammatory syndrome (IRIS) after starting antiretroviral therapy. The pathophysiology of …

Severe mycobacterial immune reconstitution inflammatory syndrome (IRIS) in advanced human immunodeficiency virus (HIV) has features of hemophagocytic …

JM Rocco, E Laidlaw, F Galindo… - Clinical Infectious …, 2023 - academic.oup.com
Background People with HIV and mycobacterial infections can develop immune
reconstitution inflammatory syndrome (IRIS) after starting antiretroviral therapy (ART) …

Platelet and ferritin as early predictive factors for the development of macrophage activation syndrome in children with Kawasaki disease: A retrospective case-control …

H Zhang, M Xiao, D Zhou, F Yan, Y Zhang - Frontiers in Pediatrics, 2023 - frontiersin.org
Objective To investigate the early predictive factors for Kawasaki disease complicated with
macrophage activation syndrome (KD-MAS) Methods We performed a retrospective case …

[PDF][PDF] Severe mycobacterial IRIS in advanced HIV has features of hemophagocytic lymphohistiocytosis and requires prolonged immune suppression

JM Rocco, E Laidlaw, F Galindo - Clin Infect Dis, 2023 - scholar.archive.org
1 2 Background: People with HIV and mycobacterial infections can develop immune
reconstitution 3 inflammatory syndrome (IRIS) after starting antiretroviral therapy. Severe …

Therapeutic plasma exchange in refractory macrophage activation syndrome complicating systemic juvenile idiopathic arthritis: a case-based review

E Liquidano-Perez, G Maza-Ramos… - Rheumatology …, 2023 - Springer
Juvenile idiopathic arthritis (JIA) is a heterogeneous group of arthritis of autoimmune
aetiology. Systemic-onset juvenile idiopathic arthritis (soJIA) presents with fever, transient …

儿童川崎病相关巨噬细胞活化综合征的临床诊治

郝胜, 黄敏 - 临床儿科杂志, 2023 - jcp.xinhuamed.com.cn
川崎病是一种系统性血管炎, 巨噬细胞活化综合征是儿童风湿性免疫疾病的危重并发症,
其发病基础为细胞因子风暴, 进展快, 病死率高, 川崎病相关巨噬细胞活化综合征早期识别困难 …