Dry eye disease: identification and therapeutic strategies for primary care clinicians and clinical specialists

J Sheppard, B Shen Lee, LM Periman - Annals of medicine, 2023 - Taylor & Francis
Dry eye disease (DED) is a multifactorial disorder characterized by loss of tear film
homeostasis with an estimated worldwide prevalence of 5% to 50%. In DED, dysfunction of …

[HTML][HTML] Tear biomarkers in dry eye disease: Progress in the last decade

NR Kumar, M Praveen, R Narasimhan… - Indian journal of …, 2023 - journals.lww.com
Dry eye disease (DED) is a commonly occurring, multifactorial disease characterized by
reduced tear film stability and hyperosmolarity at the ocular surface, leading to discomfort …

Unveiling the power of gabapentin-loaded nanoceria with multiple therapeutic capabilities for the treatment of dry eye disease

CJ Yang, A Anand, CC Huang, JY Lai - ACS nano, 2023 - ACS Publications
Dry eye (DE) disease, which is primarily linked to aqueous deficiency, is an escalating
health issue worldwide, mainly due to the widespread use of electronic devices. The major …

Berberine ameliorate inflammation and apoptosis via modulating PI3K/AKT/NFκB and MAPK pathway on dry eye

Y Han, S Guo, Y Li, J Li, L Zhu, Y Liu, Y Lv, D Yu… - Phytomedicine, 2023 - Elsevier
Background Dry eye disease (DED) is a multifactorial disease in ocular surface, and
inflammation plays an etiological role. Berberine (BBR) has shown efficacy in treating …

Prevalence of dry eye disease among individuals scheduled for cataract surgery in a Norwegian cataract clinic

P Graae Jensen, M Gundersen, C Nilsen… - Clinical …, 2023 - Taylor & Francis
Purpose To determine the prevalence of dry eye disease (DED) in patients scheduled for
cataract surgery in a Norwegian eye clinic. Patients and Methods 218 patients scheduled for …

TFOS Lifestyle-Evidence quality report: Advancing the evaluation and synthesis of research evidence

LE Downie, AC Britten-Jones, RE Hogg, I Jalbert, T Li… - The Ocular Surface, 2023 - Elsevier
Evidence-based practice is a dominant paradigm in healthcare that emphasizes the
importance of ensuring the translation of the best available, relevant research evidence into …

[HTML][HTML] The potential role of regulated cell death in dry eye diseases and ocular surface dysfunction

C Scarpellini, A Ramos Llorca, C Lanthier… - International journal of …, 2023 - mdpi.com
The research on new treatments for dry eye diseases (DED) has exponentially grown over
the past decades. The increased prevalence of dry eye conditions, particularly in the …

[HTML][HTML] Artificial intelligence-assisted diagnosis of ocular surface diseases

Z Zhang, Y Wang, H Zhang, A Samusak… - Frontiers in Cell and …, 2023 - frontiersin.org
With the rapid development of computer technology, the application of artificial intelligence
(AI) in ophthalmology research has gained prominence in modern medicine. Artificial …

[HTML][HTML] Animal models in eye research: focus on corneal pathologies

A Loiseau, G Raîche-Marcoux, C Maranda… - International Journal of …, 2023 - mdpi.com
The eye is a complex sensory organ that enables visual perception of the world. The
dysfunction of any of these tissues can impair vision. Conduction studies on laboratory …

[HTML][HTML] Dry eye disease in the young: A narrative review

F Stapleton, FG Velez, C Lau, JS Wolffsohn - The ocular surface, 2023 - Elsevier
Dry eye disease (DED), a multifactorial ocular disease that significantly impacts quality of
life, is most commonly reported in adults. This review describes the prevalence, risk factors …