Cisplatin nephrotoxicity: new insights and therapeutic implications
C Tang, MJ Livingston, R Safirstein… - Nature Reviews …, 2023 - nature.com
Cisplatin is an effective chemotherapeutic agent for various solid tumours, but its use is
limited by adverse effects in normal tissues. In particular, cisplatin is nephrotoxic and can …
limited by adverse effects in normal tissues. In particular, cisplatin is nephrotoxic and can …
Genetic variation in organic cation transporters and considerations in drug development
MVS Varma - Expert Opinion on Drug Metabolism & Toxicology, 2023 - Taylor & Francis
Introduction Membrane transporters are now widely recognized for their role in the
absorption, distribution, clearance, and elimination of drugs. The organic cation transporters …
absorption, distribution, clearance, and elimination of drugs. The organic cation transporters …
Interaction of systemic drugs causing ocular toxicity with organic cation transporter: an artificial intelligence prediction
M Malani, MS Hiremath, S Sharma… - Journal of …, 2023 - Taylor & Francis
Chronic disease patients (cancer, arthritis, cardiovascular diseases) undergo long-term
systemic drug treatment. Membrane transporters in ocular barriers could falsely recognize …
systemic drug treatment. Membrane transporters in ocular barriers could falsely recognize …
Polymorphic renal transporters and cisplatin's toxicity in urinary bladder cancer patients: current perspectives and future directions
MS Selim, AB Kassem, NA El-Bassiouny… - Medical Oncology, 2023 - Springer
Urinary bladder cancer (UBC) holds a potentially profound social burden and affects over
573,278 new cases annually. The disease's primary risk factors include occupational …
573,278 new cases annually. The disease's primary risk factors include occupational …
Cisplatin Nefrotoxicity and Treatment Approaches
N KARAGÖL - International Journal of PharmATA, 2023 - dergipark.org.tr
Cancer is one of the most important health problem in the world. Cisplatin is an effective
chemotherapeutic drug that is widely used in many cancer types such as lung, cervical …
chemotherapeutic drug that is widely used in many cancer types such as lung, cervical …