[HTML][HTML] Neuroinflammation microenvironment sharpens seizure circuit

B Villasana-Salazar, A Vezzani - Neurobiology of Disease, 2023 - Elsevier
A large set of inflammatory molecules and their receptors are induced in epileptogenic foci
of patients with pharmacoresistant epilepsies of structural etiologies or with refractory status …

Neuroimmunology of status epilepticus

A Vezzani, R Di Sapia, V Kebede, S Balosso… - Epilepsy & Behavior, 2023 - Elsevier
Status epilepticus (SE) is a very heterogeneous clinical condition often refractory to
available treatment options. Evidence in animal models shows that neuroinflammation …

[HTML][HTML] An in vitro model of drug-resistant seizures for selecting clinically effective antiseizure medications in Febrile Infection-Related Epilepsy Syndrome

M Cerovic, M Di Nunzio, I Craparotta… - Frontiers in …, 2023 - frontiersin.org
Introduction FIRES is a rare epileptic encephalopathy induced by acute unremitting seizures
that occur suddenly in healthy children or young adults after a febrile illness in the preceding …

[HTML][HTML] Insight into drug resistance in status epilepticus: evidence from animal models

F Wang, Q Zhang, Y Wang, J Chen… - International Journal of …, 2023 - mdpi.com
Status epilepticus (SE), a condition with abnormally prolonged seizures, is a severe type of
epilepsy. At present, SE is not well controlled by clinical treatments. Antiepileptic drugs …

Further advances in epilepsy

J Fawcett, S Davis, M Manford - Journal of Neurology, 2023 - Springer
In 2017, one of us reviewed advances in epilepsy (Manford in J Neurol 264: 1811–1824,
2017). The current paper brings that review up to date and gives a slight change in …

[HTML][HTML] Interleukin-1 in febrile infection-related epilepsy syndrome

JW Kang, S Koh - Annals of Child Neurology, 2023 - annchildneurol.org
Febrile infection-related epilepsy syndrome (FIRES) characteristically affects previously
healthy children, who experience a sudden and explosive onset of super-refractory status …

Febrile status epilepticus-related epilepsy: Neuroinflammation and epigenetics

T Ravizza, A Vezzani, TZ Baram - Febrile Seizures, 2023 - Elsevier
The contribution of neuroinflammatory processes to epilepsy that may follow febrile status
epilepticus (FSE) is crucial, as inflammatory mediators offer targets for prevention and …

Anakinra in Creutzfeldt-Jakob disease

G Bomboi, ML Bernardo, D Mei, NP Falcone… - Acta Neurologica …, 2023 - Springer
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