The RNA splicing process which removes introns from nascent transcripts is an
indispensable step in gene expression. The life processes of organisms are composed of a …

Amelogenin plays a crucial role in tooth enamel formation, and mutations on X-
chromosomal amelogenin cause X-linked amelogenesis imperfecta (AI). Amelogenin pre …

Spatiotemporal monitoring of multiple low-abundance messenger RNAs (mRNAs) is vitally
important for the diagnosis and pathologic analysis of cancer. However, it remains a clinical …

Objective Accumulating evidence has shown that aberrant alternative splicing events are
closely associated with the onset and development of cancer. However, whether genetic …

ABSTRACT Breast Cancer Gene 1 (BRCA1) is a tumour suppressor protein that modulates
multiple biological processes including genomic stability and DNA damage repair. Although …

Simple Summary Alternative splicing generates transcripts that can promote tumorigenesis,
but intron retention (IR), a form of alternative splicing, remains understudied. We …

Specific recognition and sensitive quantification of mRNA alternative splice variants have
been a necessity for exploring the regulatory mechanism of RNA splicing and revealing the …

Alternative messenger RNA (mRNA) splicing is a vital regulatory process during the gene
expression of higher eukaryotes. The specific and sensitive quantification of disease-related …

The process of splicing messenger RNA to remove introns plays a central role in creating
genes and gene variants. Here we describe Splam, a novel method for predicting splice …

Head and neck cancer (HNC), the sixth most common cancer globally, stands first in India,
especially Northeast India, where tobacco usage is predominant, which introduces various …