Immune responses in mildly versus critically ill COVID-19 patients

H Nasrollahi, AG Talepoor, Z Saleh… - Frontiers in …, 2023 - frontiersin.org
The current coronavirus pandemic (COVID-19), caused by SARS-CoV-2, has had
devastating effects on the global health and economic system. The cellular and molecular …

[HTML][HTML] COVID-19 and hepatic injury: cellular and molecular mechanisms in diverse liver cells

FEM Ali, MK Abd El-Aziz, MM Ali… - World Journal of …, 2023 - ncbi.nlm.nih.gov
Abstract The coronavirus disease 2019 (COVID-19) represents a global health and
economic challenge. Hepatic injuries have been approved to be associated with severe …

SARS-CoV-2 inhibits NRF2-mediated antioxidant responses in airway epithelial cells and in the lung of a murine model of infection

Y Qu, A Haas de Mello, DR Morris… - Microbiology …, 2023 - Am Soc Microbiol
Several viruses have been shown to modulate the transcription factor nuclear factor
erythroid 2-related factor 2 (NRF2), the master regulator of redox homeostasis. The severe …

[HTML][HTML] On fine particulate matter and COVID-19 spread and severity: An in vitro toxicological plausible mechanism

S Marchetti, M Gualtieri, A Pozzer, J Lelieveld… - Environment …, 2023 - Elsevier
COVID-19 pandemic had a significant impact on global public health. The spread of the
disease was related to the high transmissibility of SARS-CoV-2 virus but incidence and …

[HTML][HTML] Innate lymphoid cell plasticity in mucosal infections

AA Korchagina, E Koroleva, AV Tumanov - Microorganisms, 2023 - mdpi.com
Mucosal tissue homeostasis is a dynamic process that involves multiple mechanisms
including regulation of innate lymphoid cells (ILCs). ILCs are mostly tissue-resident cells …

Diabetic endothelial microangiopathy and pulmonary dysfunction

L Zhang, F Jiang, Y Xie, Y Mo, X Zhang… - Frontiers in …, 2023 - frontiersin.org
Type 2 diabetes mellitus (T2DM) is a widespread metabolic condition with a high global
morbidity and mortality rate that affects the whole body. Their primary consequences are …

[PDF][PDF] Comparison of treatment of COVID-19 with inhaled bromhexine, higher doses of colchicine and hymecromone with WHO-recommended paxlovid, molnupiravir …

V Mitev - Pharmacia, 2023 - pharmacia.pensoft.net
Millions of publications and thousands of clinical trials have not led to the discovery of an
effective treatment for COVID-19. We believe that the reason for this is the inaccurate …

[HTML][HTML] Antiphospholipid antibodies are enriched post-acute COVID-19 but do not modulate the thrombotic risk

M Emmenegger, V Emmenegger, SM Shambat… - Clinical …, 2023 - Elsevier
Background and objectives COVID-19-associated coagulopathy, shown to increase the risk
for the occurrence of thromboses and microthromboses, displays phenotypic features of the …

Airway Epithelial-Derived Immune Mediators in COVID-19

TJF Guo, GK Singhera, JM Leung, DR Dorscheid - Viruses, 2023 - mdpi.com
The airway epithelium, which lines the conducting airways, is central to the defense of the
lungs against inhaled particulate matter and pathogens such as SARS-CoV-2, the virus that …

[HTML][HTML] Effects of diarylbutane lignans from Schisandra chinensis fruit on SARS-CoV-2 3CLpro and PLpro and their in vitro anti-inflammatory properties

B Li, L Qiao, Q Xiao, J Zhang, J Liu, B Zhang, H Liu - Phytomedicine Plus, 2023 - Elsevier
Background Schisandra chinensis fruit is a well-known traditional Chinese medicine (TCM),
whose extract has a potent inhibitory effect on the severe acute respiratory syndrome …