The increasing prevalence of metabolic syndrome is associated with major health and
socioeconomic consequences. Currently, physical exercise, together with dietary …

Cardiovascular diseases (CVD) are among the leading causes of death worldwide. Many
lines of evidence suggest that the disturbances in circadian rhythm are responsible for the …

A different drug–drug interaction (DDI) scenario may exist in patients with chronic kidney
disease (CKD) compared with healthy volunteers (HVs), depending on the interplay …

Physiological processes occur in accordance with a rhythm regulated by the endogenous
biological clock. This clock is programmed at the molecular level and synchronized with the …

The relative risk reduction of cardiovascular events is proportional to the absolute reduction
in LDL-C levels, the primary target of therapy, no matter the way of reduction. During the last …

Background Statins have been reported to reduce the risk of gallstone disease. However,
the impacts of different durations of statin use on gallstone disease have not been clarified …

Since lipid abnormalities tend to progress from childhood to adulthood, it is necessary to
early identify and treat children and adolescents with dyslipidemia. This is important in order …

Aims More optimal dispensing of statins is associated with greater cholesterol lowering;
however, it is not known whether this translates to improved outcomes following acute …

Jessie Vitic PharmD Erin Yakiwchuk BSP ACPR MSc BCGP Alex Crawley BSP ACPR
Proper timing of medication administration can maximize effectiveness, minimize adverse …

Jessie Vitic PharmD Erin Yakiwchuk BSP ACPR MSc BCGP Alex Crawley BSP ACPR Le
choix du moment approprié pour administrer la médication peut maximiser son efficacité …