The immune-cell origin of hematologic malignancies provides a unique avenue for the
understanding of both the mechanisms of immune responsiveness and immune escape …

VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) is a novel entity
manifesting with a multiplicity of clinical features. Somatic mutations of the UBA1 gene in …

Background CPX-351, an encapsulated form of cytarabine and daunorubicin, has shown
greater efficacy than the classic 3+ 7 treatment administration in secondary acute myeloid …

Myelodysplastic syndromes (MDS) are a heterogenous group of clonal hematopoietic stem
cell neoplasms primarily affecting older persons, associated with dysplastic changes of bone …

Abstract We compared FT14 (fludarabine 150–160 mg/m2, treosulfan 42 g/m2) versus FB4
(fludarabine 150–160 mg/m2, busulfan 12.8 mg/kg) in acute myeloid leukemia (AML) …

Although the use of allogeneic hematopoietic cell transplantation (HCT) for chronic
lymphocytic leukemia (CLL) has declined with the development of novel targeted agents, it …

We conducted a registry analysis including adult acute myeloid leukemia (AML) patients in
remission who had received thiotepa, busulfan, and fludarabine (TBF) or treosulfan-based …

Treosulfan is a structural analog of the alkylating agent busulfan which has been shown in
clinical trials to exhibit comparable myeloablative activity while causing fewer serious side …

Intravenously infused treosulfan was evaluated in adult and pediatric patients for
conditioning regimen prior to allogeneic hematopoietic stem cell transplantation. A …

Amaç: Biz bu çalışmada 60 yaş ve üzerindeki hematolojik malignitesi olan hastalarda allo-
HSCT deneyimini ve sonuçlarını sunmayı amaçladık. Gereç ve yöntemler: 2017-2021 yılları …