Neurodegenerative disorders are characterized by the progressive dysfunction and death of
selectively vulnerable neuronal populations, often associated with the accumulation of …

Therapeutic strategies for neurodegenerative disorders have commonly targeted individual
aspects of the disease pathogenesis to little success. Neurodegenerative diseases …

Epilepsy is a neurological disorder that poses a major threat to public health.
Hyperactivation of mTOR complex 1 (mTORC1) is believed to lead to abnormal network …

Background Recent studies have suggested an association between gut microbiomes
(GMs) and epilepsy. However, the GM taxa identified in different studies are variable. In …

Transportation noise is a ubiquitous urban exposure. In 2018, the World Health Organization
concluded that chronic exposure to road traffic noise is a risk factor for ischemic heart …

Microglial phagocytosis of apoptotic debris prevents buildup damage of neighbor neurons
and inflammatory responses. Whereas microglia are very competent phagocytes under …

The transplantation of mesenchymal stem cells-derived secretome, particularly extracellular
vesicles is a promising therapy to suppress spinal cord injury-triggered neuroinflammation …

Background Limited progress in terms of an effective treatment for spinal cord injury (SCI)
emphasizes the urgent need for novel therapies. As a vital central nervous system …

BACKGROUND: An understanding of global, regional, and national macroeconomic losses
caused by stroke is important for allocation of clinical and research resources. The authors …

Parkinson's disease (PD) is a progressive neurodegenerative disorder that primarily affects
elderly people and constitutes a major source of disability worldwide. Notably, the …