Nicotinamide adenine dinucleotide (NAD+) is a ubiquitous metabolite that takes part in
many key redox reactions. NAD+ biosynthesis and NAD+-consuming enzymes have been …

The importance of nicotinamide adenine dinucleotide (NAD+) in human physiology is well
recognized. As the NAD+ concentration in human skin, blood, liver, muscle and brain are …

Purpose of Review NAD+ is a vital molecule that takes part as a redox cofactor in several
metabolic reactions besides being used as a substrate in important cellular signaling in …

Multiple myeloma (MM) is an incurable plasma cell malignancy, which is predominantly a
disease of older adults (the median age at diagnosis is 70 years). The slow progression from …

Skeletal muscle is a tissue integral to general health. Due to its high abundance and
oxidative capacity, its metabolism is intimately linked to whole-body physiology. In the …

Hepatitis A virus (HAV) infection often causes acute hepatitis, which results in a case fatality
rate of 0.2% and fulminant hepatitis in 0.5% of cases. However, no specific potent anti-HAV …

Life expectancy is increasing throughout the world and coincides with a rise in non-
communicable diseases (NCDs), especially for metabolic disease that includes diabetes …

As a significant non-communicable disease, cardiovascular disease is the leading cause of
death for both men and women, comprises almost twenty percent of deaths in most racial …

The ability of cells to store and rapidly mobilize energy reserves in response to nutrient
availability is essential for survival. Breakdown of carbon stores produces acetyl-CoA …

Abstract Lysine 2‐hydroxyisobutyrylation (Khib) is a novel protein post‐translational
modifications (PTMs) observed in both eukaryotes and prokaryotes. Recent studies …