Gut microbiome lipid metabolism and its impact on host physiology

EM Brown, J Clardy, RJ Xavier - Cell Host & Microbe, 2023 - cell.com
Metabolites produced by commensal gut microbes impact host health through their
recognition by the immune system and their influence on numerous metabolic pathways …

Human metabolome variation along the upper intestinal tract

J Folz, RN Culver, JM Morales, J Grembi… - Nature …, 2023 - nature.com
Most processing of the human diet occurs in the small intestine. Metabolites in the small
intestine originate from host secretions, plus the ingested exposome and microbial …

Membrane lipids from gut microbiome-associated bacteria as structural and signalling molecules

E Ryan, SA Joyce, DJ Clarke - Microbiology, 2023 - microbiologyresearch.org
Bacteria produce an array of diverse, dynamic and often complex lipid structures, some of
which function beyond their typical role in membrane structure. The model organism, E. coli …

Role and interaction of bacterial sphingolipids in human health

X Bai, R Ya, X Tang, M Cai - Frontiers in Microbiology, 2023 - frontiersin.org
Sphingolipids, present in both higher animals and prokaryotes, involving in cell
differentiation, pathogenesis and apoptosis in human physiological health. With increasing …

Biosynthetic Enzyme-guided Disease Correlation Connects Gut Microbial Metabolites Sulfonolipids to Inflammatory Bowel Disease Involving TLR4 Signaling

EA Older, J Zhang, ZE Ferris, D Xue, Z Zhong… - bioRxiv, 2023 - biorxiv.org
The trillions of microorganisms inhabiting the human gut are intricately linked to human
health. At the species abundance level, correlational studies have connected specific …

[引用][C] Human Gut Microbial Sulfonolipids are linked to Inflammatory Bowel Diseases through Toll-Like Receptor 4 Signaling

EA Older, J Zhang, ZE Ferris, D Xue, Z Zhong…