[HTML][HTML] Neurodegenerative and neurodevelopmental diseases and the gut-brain axis: The potential of therapeutic targeting of the microbiome

B Bicknell, A Liebert, T Borody, G Herkes… - International Journal of …, 2023 - mdpi.com
The human gut microbiome contains the largest number of bacteria in the body and has the
potential to greatly influence metabolism, not only locally but also systemically. There is an …

[HTML][HTML] The interaction between mushroom polysaccharides and gut microbiota and their effect on human health: A review

J Zhao, Y Hu, C Qian, M Hussain, S Liu, A Zhang, R He… - Biology, 2023 - mdpi.com
Simple Summary A growing number of studies have shown that mushroom polysaccharides
could exert anti-diabetes, anti-intestinal inflammation and antitumor effects by regulating gut …

[HTML][HTML] Probiotics as functional foods: How probiotics can alleviate the symptoms of neurological disabilities

S Aghamohammad, A Hafezi, M Rohani - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Neurological disorders are diseases of the central nervous system with progressive loss of
nervous tissue. One of the most difficult problems associated with neurological disorders is …

[HTML][HTML] Probiotics supplementation attenuates inflammation and oxidative stress induced by chronic sleep restriction

Y Zheng, L Zhang, L Bonfili, L de Vivo, AM Eleuteri… - Nutrients, 2023 - mdpi.com
Background: Insufficient sleep is a serious public health problem in modern society. It leads
to increased risk of chronic diseases, and it has been frequently associated with cellular …

Association of gut microbiota with COVID‐19 susceptibility and severity: a two‐sample Mendelian randomization study

W Shang, S Zhang, H Qian, X Pan… - Journal of Medical …, 2023 - Wiley Online Library
Evidence supports the observational associations of gut microbiota with the risk of COVID‐
19; however, it is unclear whether these associations reflect a causal relationship. This study …

[HTML][HTML] Neurotrophic factor-based pharmacological approaches in neurological disorders

M Alfonsetti, M d'Angelo, V Castelli - Neural regeneration …, 2023 - journals.lww.com
Aging is a physiological event dependent on multiple pathways that are linked to lifespan
and processes leading to cognitive decline. This process represents the major risk factor for …

[HTML][HTML] Bacterial Lysate from the Multi-Strain Probiotic SLAB51 Triggers Adaptative Responses to Hypoxia in Human Caco-2 Intestinal Epithelial Cells under …

F Lombardi, FR Augello, P Palumbo, L Bonfili… - International Journal of …, 2023 - mdpi.com
Hypoxia-inducible factor-1α (HIF-1α), a central player in maintaining gut-microbiota
homeostasis, plays a pivotal role in inducing adaptive mechanisms to hypoxia and is …

The gut microbiome: an important role in neurodegenerative diseases and their therapeutic advances

S Li, L Zhao, J Xiao, Y Guo, R Fu, Y Zhang… - Molecular and cellular …, 2023 - Springer
There are complex interactions between the gut and the brain. With increasing research on
the relationship between gut microbiota and brain function, accumulated clinical and …

[HTML][HTML] Mesenchymal stem cell secretome and extracellular vesicles for neurodegenerative diseases: Risk-benefit profile and next steps for the market access

L Giovannelli, E Bari, C Jommi, F Tartara, D Armocida… - Bioactive Materials, 2023 - Elsevier
Neurodegenerative diseases represent a growing burden on healthcare systems worldwide.
Mesenchymal stem cells (MSCs) have shown promise as a potential therapy due to their …

Heat‐killed Lactobacillus murinus confers neuroprotection against dopamine neuronal loss by targeting NLRP3 inflammasome

HX Fan, S Sheng, DD Li, JJ Li… - Bioengineering & …, 2023 - Wiley Online Library
The intestinal flora has become very active in studies related to Parkinson's disease (PD) in
recent years. The microbe‐gut‐brain axis is closely related to the maintenance of brain …