Opening the black box: why do euploid blastocysts fail to implant? A systematic review and meta-analysis

D Cimadomo, L Rienzi, A Conforti… - Human …, 2023 - academic.oup.com
BACKGROUND A normal chromosomal constitution defined through PGT-A assessing all
chromosomes on trophectoderm (TE) biopsies represents the strongest predictor of embryo …

[HTML][HTML] Recurrent implantation failure: reality or a statistical mirage?: consensus statement from the July 1, 2022 Lugano Workshop on recurrent implantation failure

P Pirtea, MI Cedars, K Devine, B Ata, J Franasiak… - Fertility and sterility, 2023 - Elsevier
Importance To date, recurrent implantation failure (RIF) has no clear definition and no clearly
identified impaired function. Hence, the term RIF is currently used somewhat haphazardly …

[PDF][PDF] Recurrent MiscarriageGreen‐top Guideline No. 17

L Regan, R Rai, S Saravelos, TC Li… - … Journal of Obstetrics …, 2023 - missionmrcog.com
• In this guideline, recurrent miscarriage has been defined as three or more first trimester
miscarriages. However, clinicians are encouraged to use their clinical discretion to …

Good practice recommendations on add-ons in reproductive medicine

ESHRE Add-ons working group, K Lundin… - Human …, 2023 - academic.oup.com
STUDY QUESTION Which add-ons are safe and effective to be used in ART treatment?
SUMMARY ANSWER Forty-two recommendations were formulated on the use of add-ons in …

Endometrial scratching in women undergoing IVF/ICSI: an individual participant data meta-analysis

NE Van Hoogenhuijze… - Human reproduction …, 2023 - academic.oup.com
Abstract BACKGROUND In IVF/ICSI treatment, the process of embryo implantation is the
success rate-limiting step. Endometrial scratching has been suggested to improve this …

[HTML][HTML] Immunomodulation for unexplained recurrent implantation failure: where are we now?

G Genest, S Banjar, W Almasri, C Beauchamp… - …, 2023 - rep.bioscientifica.com
In brief Immune dysfunction may contribute to or cause recurrent implantation failure. This
article summarizes normal and pathologic immune responses at implantation and critically …

[HTML][HTML] The role of endometrial scratching prior to in vitro fertilization: an updated systematic review and meta-analysis

MC Iakovidou, E Kolibianakis, L Zepiridis… - Reproductive Biology …, 2023 - Springer
Research question To evaluate the role of endometrial scratching performed prior to an
embryo transfer cycle on the probability of pregnancy compared to placebo/sham or no …

Determinants of embryo implantation: roles of the endometrium and embryo in implantation success

AO Awonuga, OG Camp, HM Abu-Soud… - Reproductive …, 2023 - Springer
Both uterine endometrium and embryo contribute to implantation success. However, their
relative role in the implantation success is still a matter for debate, as are the roles of …

Endometrial receptivity, to test or not to test: the evidence on contemporary assays

E Clain, K Devine - F&S Reviews, 2023 - Elsevier
Despite improvements in in vitro fertilization success over the last 2 decades, the live birth
rates do not exceed 65% even after transfer of a preimplantation genetic testing for …

Patient informed choice in the age of evidence‐based medicine: IVF patients' approaches to biomedical evidence and fertility treatment add‐ons

M Perrotta, J Hamper - Sociology of Health & Illness, 2023 - Wiley Online Library
With the increasing offer of fertility treatment by a largely privatised sector, which has
involved the proliferation of treatment add‐ons lacking evidence of effectiveness, In‐Vitro …