Boquila: NGS read simulator to eliminate read nucleotide bias in sequence analysis
Sequence content is heterogeneous throughout genomes. Therefore, genome-wide next-
generation sequencing (NGS) reads biased towards specific nucleotide profiles are affected …
generation sequencing (NGS) reads biased towards specific nucleotide profiles are affected …
Synggen: fast and data-driven generation of synthetic heterogeneous NGS cancer data
R Scandino, F Calabrese, A Romanel - Bioinformatics, 2023 - academic.oup.com
Whole-exome and targeted sequencing are widely utilized both in translational cancer
genomics and in the setting of precision medicine. The benchmarking of computational …
genomics and in the setting of precision medicine. The benchmarking of computational …