Mice and rats emit ultrasonic vocalizations (USVs), which may express their arousal and
emotional states, to communicate with each other. There is continued scientific effort to …

The mechanisms underlying phenotypic heterogeneity in autism spectrum disorder (ASD)
are not well understood. Using a large neuroimaging dataset, we identified three latent …

Idiopathic autism spectrum disorder (ASD) is highly heterogeneous, and it remains unclear
how convergent biological processes in affected individuals may give rise to symptoms …

Microglia are the brain's resident macrophages, which guide various developmental
processes crucial for brain maturation, activity, and plasticity. Microglial progenitors enter the …

The development of the human brain involves unique processes (not observed in many
other species) that can contribute to neurodevelopmental disorders,,–. Cerebral organoids …

Advancing from gene discovery in autism spectrum disorders (ASDs) to the identification of
biologically relevant mechanisms remains a central challenge. Here, we perform parallel in …

We analyzed> 700,000 single-nucleus RNA sequencing profiles from 106 donors during
prenatal and postnatal developmental stages and identified lineage-specific programs that …

Autism spectrum disorders (ASDs) have been linked to genes with enriched expression in
the brain, but it is unclear how these genes converge into cell-type-specific networks. We …

Major depressive disorder (MDD) is one of the most important causes of disability
worldwide. While recent work provides insights into the molecular alterations in the brain of …

Autism spectrum disorders (ASDs) include a wide range of neurodevelopmental disorders.
Several reports showed that mutations in different high‐risk ASD genes lead to ASD …