Major depressive disorder (MDD) is a complex and heterogeneous psychiatric syndrome
with genetic and environmental influences. In addition to neuroanatomical and circuit-level …

Children who experience adversities have an elevated risk of mental health problems.
However, the extent to which adverse childhood experiences (ACEs) cause mental health …

Exposure to stressful life events increases the risk for psychiatric disorders. Mechanistic
insight into the genetic factors moderating the impact of stress can increase our …

Stress and psychiatric disorders have been independently associated with disruption of the
maternal and offspring microbiome, and with increased risk of the offspring developing …

Behavior genetics is a controversial science. For decades, scholars have sought to
understand the role of heredity in human behavior and life-course outcomes. Recently …

Objective: Despite substantial progress in identifying genomic variation associated with
major depression, the mechanisms by which genomic and environmental factors jointly …

Genetic factors contribute significantly to interindividual differences in the susceptibility to
stress‐related disorders. As stress can also be conceptualized as environmental exposure …

Deficits in cognitive function and memory are common early symptoms of
neurodegenerative disorders, such as Alzheimer's Disease (AD). Several studies have …

Background Converging evidence suggests that elevated inflammation may contribute to
depression. Yet, the link between peripheral inflammation and neuroinflammation in …

Aims Childhood trauma has been associated with adult psychosocial outcomes linked to
social exclusion. However, the strength of these associations in the general population is …