Mutations causing dysfunction of tubulins and microtubule-associated proteins, also known
as tubulinopathies, are a group of recently described entities that lead to complex brain …

Objective Congenital hypogonadotropic hypogonadism (CHH) is a rare, genetically
heterogeneous reproductive disorder caused by gonadotropin-releasing hormone (GnRH) …

During embryonic development, the olfactory placode (OP) generates migratory neurons,
including olfactory pioneer neurons, cells of the terminal nerve (TN), Gonadotropin-releasing …

In cells, microtubule location, length, and dynamics are regulated by a host of microtubule-
associated proteins and enzymes that read where to bind and act based on the microtubule …

Background and Purpose Möbius sequence (MBS) previously known as Möbius syndrome
is a rare nonprogressive developmental defect of the rhombencephalon leading to …

Neuronal migration and axon growth and guidance require precise control of microtubule
dynamics and microtubule-based cargo transport. TUBB3 encodes the neuronal-specific β …

A baby boy presented to the ophthalmology clinic at age 2 months of age with poor visual
behavior. His parents reported that he did not seem to fix and follow objects, or to respond to …