The roles of critical pro‐inflammatory cytokines in the drive of cytokine storm during SARS‐CoV‐2 infection

MS Qudus, M Tian, S Sirajuddin, S Liu… - Journal of Medical …, 2023 - Wiley Online Library
In patients with severe COVID‐19, acute respiratory distress syndrome (ARDS), multiple
organ dysfunction syndrome (MODS), and even mortality can result from cytokine storm …

Neutrophil activation and neutrophil extracellular traps (NETs) in COVID‐19 ARDS and immunothrombosis

MC Cesta, M Zippoli, C Marsiglia… - European Journal of …, 2023 - Wiley Online Library
Acute respiratory distress syndrome (ARDS) is an acute inflammatory condition with a
dramatic increase in incidence since the beginning of the coronavirus disease 19 (COVID …

Autoimmune and autoinflammatory connective tissue disorders following COVID-19

SH Lim, HJ Ju, JH Han, JH Lee, WS Lee… - JAMA network …, 2023 - jamanetwork.com
Importance Multiple cases of autoimmune and autoinflammatory diseases after COVID-19
have been reported. However, their incidences and risks have rarely been quantified …

Emerging aspects of cytokine storm in COVID-19: The role of proinflammatory cytokines and therapeutic prospects

R Dharra, AK Sharma, S Datta - Cytokine, 2023 - Elsevier
COVID-19 has claimed millions of lives during the last 3 years since initial cases were
reported in Wuhan, China, in 2019. Patients with COVID-19 suffer from severe pneumonia …

COVID-19 complications: oxidative stress, inflammation, and mitochondrial and endothelial dysfunction

E Georgieva, J Ananiev, Y Yovchev… - International Journal of …, 2023 - mdpi.com
SARS-CoV-2 infection, discovered and isolated in Wuhan City, Hubei Province, China,
causes acute atypical respiratory symptoms and has led to profound changes in our lives …

ISG15: its roles in SARS-CoV-2 and other viral infections

L Sarkar, GQ Liu, MU Gack - Trends in Microbiology, 2023 - cell.com
Abstract Interferon (IFN)-stimulated gene 15 (ISG15), a ubiquitin-like pleiotropic protein and
one of the most abundant ISGs, has been studied extensively; however, its roles in SARS …

A review of RRx-001: a late-stage multi-indication inhibitor of NLRP3 activation and chronic inflammation

N Jayabalan, B Oronsky, P Cabrales, T Reid, S Caroen… - Drugs, 2023 - Springer
Chronic unresolving inflammation is emerging as a key underlying pathological feature of
many if not most diseases ranging from autoimmune conditions to cardiometabolic and …

Modeling heart diseases on a chip: advantages and future opportunities

O Mourad, R Yee, M Li, SS Nunes - Circulation Research, 2023 - Am Heart Assoc
Heart disease is a significant burden on global health care systems and is a leading cause
of death each year. To improve our understanding of heart disease, high quality disease …

The role of SARS-CoV-2 N protein in diagnosis and vaccination in the context of emerging variants: Present status and prospects

W Song, Z Fang, F Ma, J Li, Z Huang, Y Zhang… - Frontiers in …, 2023 - frontiersin.org
Despite many countries rapidly revising their strategies to prevent contagions, the number of
people infected with Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …

Exploring the role of immune system and inflammatory cytokines in SARS-CoV-2 induced lung disease: a narrative review

C Tirelli, M De Amici, C Albrici, S Mira, G Nalesso, B Re… - Biology, 2023 - mdpi.com
Simple Summary Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is
responsible for the pandemic coronavirus disease-2019 (COVID-19), which can lead to …