Decoding Connectivity Map-based drug repurposing for oncotherapy

Y Zhao, X Chen, J Chen, X Qi - Briefings in Bioinformatics, 2023 - academic.oup.com
The rising global burden of cancer has driven considerable efforts into the research and
development of effective anti-cancer agents. Fortunately, with impressive advances in …

Drug repositioning in thyroid cancer treatment: the intriguing case of anti-diabetic drugs

A Greco, F Coperchini, L Croce, F Magri… - Frontiers in …, 2023 - frontiersin.org
Cancer represents the main cause of death worldwide. Thyroid cancer (TC) shows an
overall good rate of survival, however there is a percentage of patients that do not respond …

[HTML][HTML] A precision medicine approach to personalized prescribing using genetic and nongenetic factors for clinical decision-making

S Jamrat, C Sukasem, L Sratthaphut… - Computers in Biology …, 2023 - Elsevier
Screening potential drug–drug interactions, drug–gene interactions, contraindications, and
other factors is crucial in clinical practice. However, implementing these screening concepts …

Computational Approaches for Predicting Drug-Disease Associations: A Comprehensive Review

C Ao, Z Xiao, L Guan, L Yu - arXiv preprint arXiv:2309.06388, 2023 - arxiv.org
In recent decades, traditional drug research and development have been facing challenges
such as high cost, long timelines, and high risks. To address these issues, many …

[PDF][PDF] An Ontology for Mammography Screening Recommendation.

C Acuña, Y Anchén, E Rohrer, R Motz - ICBO, 2023 - ceur-ws.org
This article presents the development of a simple Mammography Screening Ontology
(MAMO-SCR-Onto) designed to provide mammography application recommendations for …

In silico pharmacology and drug repurposing approaches

G Parmar, JM Chudasama, A Shah, A Patel - CADD and Informatics in …, 2023 - Springer
Drug repurposing is an innovative and resourceful approach to expanding access to
treatment options by making new uses for medications that are already on the market and in …

Automating the Annotation of Data through Machine Learning and Semantic Technologies

LAK Pigott-Dix - 2023 - ueaeprints.uea.ac.uk
The ever-increasing scale and complexity of scientific research is surpassing our means to
assimilate newly produced knowledge. Computer tools are necessary for the organisation …