Glutathione-related enzymes and proteins: a review

J Vašková, L Kočan, L Vaško, P Perjési - Molecules, 2023 - mdpi.com
The tripeptide glutathione is found in all eukaryotic cells, and due to the
compartmentalization of biochemical processes, its synthesis takes place exclusively in the …

Natural compounds and glutathione: Beyond mere antioxidants

C Di Giacomo, GA Malfa, B Tomasello, S Bianchi… - Antioxidants, 2023 - mdpi.com
The tripeptide glutathione plays important roles in many cell processes, including
differentiation, proliferation, and apoptosis; in fact, disorders in glutathione homeostasis are …

Naphthalimide fluorescent skeleton for facile and accurate quantification of glutathione

F Zhang, F Chen, R Shen, Y Chen, Z Zhao… - Analytical …, 2023 - ACS Publications
Glutathione (GSH), the most prevalent nonprotein thiol in biological systems, acts as both an
antioxidant to manipulate intracellular redox homeostasis and a nucleophile to detoxify …

Glutathione treatment suppresses the adverse effects of microplastics in rice

F Chen, M Aqeel, N Khalid, MK Irshad, F Farhat… - Chemosphere, 2023 - Elsevier
Oryza sativa is grown worldwide and exhibit sensitivity to different stresses. Exponential
increase in microplastics in agroecosystems is damaging and demand pragmatic strategies …

Glutathione-activated emission of ultrasmall gold nanoparticles in the second near-infrared window for imaging of early kidney injury

Z Zhao, H Chen, K He, J Lin, W Cai, Y Sun… - Analytical …, 2023 - ACS Publications
Biomarker-activatable luminescent probes with high sensitivity and specificity show great
promise in advanced bioimaging applications. However, the lack of stable biomarkers at an …

[HTML][HTML] Hydrogen sulfide donor AP123 restores endothelial nitric oxide-dependent vascular function in hyperglycemia via a CREB-dependent pathway

R Montanaro, V Vellecco, R Torregrossa, GM Casillo… - Redox Biology, 2023 - Elsevier
Diabetes is associated with severe vascular complications involving the impairment of
endothelial nitric oxide synthase (eNOS) as well as cystathionine γ-lyase (CSE) activity …

Microbial impact to environmental toxicants Ni (II) and Co (II): Joint toxicity and cellular response in Paramecium

DLG Amaya, A Thiel, M Möller, G Gasparoni… - Chemosphere, 2023 - Elsevier
Abstract Cobalt (Co) and Nickel (Ni) are increasingly found in our environment. We analysed
their combined toxicity and uptake mechanisms in the early food chain by studying bacteria …

The Combination of a Human Biomimetic Liver Microphysiology System with BIOLOGXsym, a Quantitative Systems Toxicology (QST) Modeling Platform for …

JJ Beaudoin, L Clemens, MT Miedel, A Gough… - International Journal of …, 2023 - mdpi.com
Biologics address a range of unmet clinical needs, but the occurrence of biologics-induced
liver injury remains a major challenge. Development of cimaglermin alfa (GGF2) was …

Antioxidant and photoprotective role of latex C-serum from Hevea brasiliensis during 15-week UVB irradiation in male hairless SKH-1 mice

LE Kerche, IM Carrara, PC Marinello… - Journal of Toxicology …, 2023 - Taylor & Francis
It is known that UVB radiation induces several adverse skin alterations starting from simple
photoaging to skin cancer. In addition, it was demonstrated that reactive oxygen species …

Subchronic toxicity of iron-selenium nanoparticles on oxidative stress response, histopathological, and nuclear damage in amphibian larvae Rana saharica

ER Meddeb, F Trea, A Djekoun, H Nasri… - … Science and Pollution …, 2023 - Springer
In this work, we evaluated the subchronic toxicity of FeSe nanoparticles (NPs) in tadpoles of
Rana saharica. Tadpoles were exposed for 1–3 weeks to FeSe NPs at 5 mg/L and 100 mg/L …