Liver-derived metabolites as signaling molecules in fatty liver disease

U Keles, JR Ow, KB Kuentzel, LN Zhao… - Cellular and Molecular …, 2023 - Springer
Excessive fat accumulation in the liver has become a major health threat worldwide.
Unresolved fat deposition in the liver can go undetected until it develops into fatty liver …

Sphingolipid metabolism in brain insulin resistance and neurological diseases

M Mei, M Liu, Y Mei, J Zhao, Y Li - Frontiers in Endocrinology, 2023 - frontiersin.org
Sphingolipids, as members of the large lipid family, are important components of plasma
membrane. Sphingolipids participate in biological signal transduction to regulate various …

The impact of phytochemicals in obesity-related metabolic diseases: focus on ceramide metabolism

E Kim, S Jeon - Nutrients, 2023 - mdpi.com
The prevalence of obesity and related metabolic diseases has increased dramatically
worldwide. As obesity progresses, various lipid species accumulate in ectopic tissues …

Identification of a specific plasma sphingolipid profile in a group of normal-weight and obese subjects: a novel approach for a “biochemical” diagnosis of metabolic …

AE Rigamonti, M Dei Cas, D Caroli, A De Col… - International Journal of …, 2023 - mdpi.com
Metabolic syndrome is nosographically defined by using clinical diagnostic criteria such as
those of the International Diabetes Federation (IDF) ones, including visceral adiposity, blood …

Ceramides and metabolic profiles of patients with acute coronary disease: a cross-sectional study

L Zhang, D Tan, Y Zhang, Y Ding, H Liang… - Frontiers in …, 2023 - frontiersin.org
Metabolic Syndrome (MS) is a rapidly growing medical problem worldwide and is
characterized by a cluster of age-related metabolic risk factors. The presence of MS …

[HTML][HTML] Imaging-based chromatin and epigenetic age, ImAge, quantitates aging and rejuvenation

M Alvarez-Kuglen, D Rodriguez, H Qin… - Research …, 2023 - ncbi.nlm.nih.gov
Biomarkers of biological age that predict the risk of disease and expected lifespan better
than chronological age are key to efficient and cost-effective healthcare 1–3. To advance a …

Sphingolipides: nouveaux régulateurs de la masse et de la fonction musculaire?

B Lair - 2023 - theses.hal.science
La préservation de la masse et de la force musculaire est un enjeu majeur dans de
nombreux contextes physiopathologiques. L'atrophie musculaire est une complication de …

Development of Mass Spectrometric Methods for Analysis of Sphingolipids and Oligonucleotides

AQ Tran - 2023 - archive.hshsl.umaryland.edu
Mass Spectrometry (MS) is a powerful method for analysis of biomolecules due to its
selective and sensitive analytical benchmarks, providing information about their structures …