An updated version of this article was published on 19 September 2023. This article has
been corrected. The original version of the article and supplement (PDF) is appended to this …

Introduction Drug repositioning is a strategy to identify a new therapeutic indication for
molecules that have been approved for other conditions, aiming to speed up the traditional …

Background: Previous trials have demonstrated the effects of fluvoxamine alone and inhaled
budesonide alone for prevention of disease progression among outpatients with COVID-19 …

An updated version of this article was published on 19 September 2023. Description:
Strategies to manage COVID-19 in the outpatient setting continue to evolve as new data …

This COVID‐19 outpatient randomized controlled trials (RCTs) systematic review compares
hospitalization outcomes amongst four treatment classes over pandemic period, geography …

Despite the fact that coronavirus disease 2019 (COVID-19) treatment and management are
now considerably regulated, severe acute respiratory syndrome coronavirus 2 (SARS-CoV …

Background SARS-CoV-2-mediated COVID-19 may cause sudden cardiac death (SCD).
Factors contributing to this increased risk of potentially fatal arrhythmias include thrombosis …

Hydroxychloroquine (HCQ) was initially promoted as an oral therapy for early treatment of
coronavirus disease 2019 (COVID‐19). Conventional meta‐analyses cannot fully address …

Objectives Effective and widely available therapies are still needed for outpatients with
COVID-19. We aimed to evaluate the efficacy and safety of lopinavir/ritonavir (LPV/r) for …

Under exceptional circumstances, including high rates of protocol non-compliance, per-
protocol (PP) analysis can better indicate the real-world benefits of a medical intervention …