Corals live in a complex, multipartite symbiosis with diverse microbes across kingdoms,
some of which are implicated in vital functions, such as those related to resilience against …

Molecular interaction networks lay the foundation for studying how biological functions are
controlled by the complex interplay of genes and proteins. Investigating perturbed processes …

Causal learning is a key challenge in scientific artificial intelligence as it allows researchers
to go beyond purely correlative or predictive analyses towards learning underlying cause …

Everything is connected and thus networks are instrumental in not only modeling complex
systems with many components, but also accommodating knowledge about their …

Secondary mutation, T790M, conferring tyrosine kinase inhibitors (TKIs) resistance beyond
oncogenic epidermal growth factor receptor (EGFR) mutations presents a challenging unmet …

The DNA damage response (DDR) ensures error-free DNA replication and transcription and
is disrupted in numerous diseases. An ongoing challenge is to determine the proteins …

The aberrant protein sorting has been observed in many conditions, including complex
diseases, drug treatments, and environmental stresses. It is important to systematically …

Background Some phenotypical changes may be related to changes in the associations
among genes. The set of such associations is referred to as gene interaction (or association) …

Resistance to M. tuberculosis, often referred to as “RSTR” in the literature, is being
increasingly studied because of its potential relevance as a clinical outcome in vaccine …

Robust identification of context-specific network features that control cellular phenotypes
remains a challenge. We here introduce MOBILE (Multi-Omics Binary Integration via Lasso …