Oral administration is perhaps the most commonly used and acceptable route for drug
delivery to patients, mainly due to its non-invasiveness, simplicity, and versatility …

Obesity is a complex metabolic condition that can have a negative impact on one's health
and even result in mortality. The management of obesity has been addressed in a number of …

A mechanistic understanding of how microbial proteins affect the host could yield deeper
insights into gut microbiota–host cross-talk. We developed an enzyme activity–screening …

Obesity and type 2 diabetes (T2DM) are major public health concerns associated with
serious morbidity and increased mortality. Both obesity and T2DM are strongly associated …

Introduction Evidence from cardiovascular outcome trials (CVOTs) for newer antidiabetic
drugs is increasingly influencing revised recommendations for second-line therapy in type 2 …

Introduction Liraglutide effectively controls blood glucose level and reduces body weight.
The aim of this study was to compare the efficacy and safety of a biosimilar liraglutide …

Background To determine whether glucagon-like peptide 1 receptor agonists (GLP-1RAs)
have cardiovascular and renal protective effects in patients with advanced diabetic kidney …

Background Sodium-glucose cotransporter-2 inhibitors (SGLT2i) and glucagon-like peptide-
1 receptor agonists (GLP1RA) are increasingly recommended in type 2 diabetes …

The gold standard for investigating the efficacy of a new therapy is a (pragmatic) randomized
controlled trial (RCT). This approach is costly, time‐consuming, and not always practicable …

Diabetes mellitus (DM) is a chronic metabolic disorder, with type 2 diabetes (T2DM)
significantly impacting the cardiovascular (CV) system. Our comprehensive study on the …