Many different lifestyle factors and chemicals present in the environment are a threat to the
reproductive tracts of humans. The potential for parental preconception exposure to alter …

PEG10 and PEG11/RTL1 are paternally expressed, imprinted genes that play essential
roles in the current eutherian developmental system and are therefore associated with …

Abstract microRNA-122 (miR-122) is a highly conserved microRNA that is predominantly
expressed in the liver and plays a critical role in the regulation of liver metabolism. Recent …

Background Breast cancer is the global leading cancer burden in women and the hormone
receptor-positive (HR+) subtype is a major part of breast cancer. Though cyclin-dependent …

Hypopharyngeal carcinoma is a cancer with the worst prognosis. We constructed the first
single-cell transcriptome map for hypopharyngeal carcinoma and explored its underlying …

Thousands of RNA-binding proteins (RBPs) crosslink to cellular mRNA. Among these are
numerous unconventional RBPs (ucRBPs)—proteins that associate with RNA but lack …

Introduction Retinoblastoma (RB) is the most common childhood tumor that can occur in the
retina and develop in a sporadic or heritable form. Although various traditional treatment …

Transposable elements can cause catastrophic genomic instability and are tightly regulated
by the host through multiple restriction pathways. Domesticated elements are derived from …

Osteosarcoma prognosis has remained unchanged for the past three decades. In both
humans and canines, treatment is limited to excision, radiation, and chemotherapy …

Background Preeclampsia is a severe complication of pregnancy which is attributed to
placental dysfunction. The retrotransposon, Paternal Expressed Gene 10 (PEG10) harbours …