Pathogenicity of Type I Interferons in Mycobacterium tuberculosis
A Mundra, A Yegiazaryan, H Karsian, D Alsaigh… - International Journal of …, 2023 - mdpi.com
Tuberculosis (TB) is a leading cause of mortality due to infectious disease and rates have
increased during the emergence of COVID-19, but many of the factors determining disease …
increased during the emergence of COVID-19, but many of the factors determining disease …
[HTML][HTML] Mycobacterium tuberculosis suppresses host DNA repair to boost its intracellular survival
S Liu, L Guan, C Peng, Y Cheng, H Cheng, F Wang… - Cell Host & Microbe, 2023 - cell.com
Mycobacterium tuberculosis (Mtb) triggers distinct changes in macrophages, resulting in the
formation of lipid droplets that serve as a nutrient source. We discover that Mtb promotes …
formation of lipid droplets that serve as a nutrient source. We discover that Mtb promotes …
Early cellular mechanisms of type I interferon-driven susceptibility to tuberculosis
DI Kotov, OV Lee, SA Fattinger, CA Langner, JV Guillen… - Cell, 2023 - cell.com
Summary Mycobacterium tuberculosis (Mtb) causes 1.6 million deaths annually. Active
tuberculosis correlates with a neutrophil-driven type I interferon (IFN) signature, but the …
tuberculosis correlates with a neutrophil-driven type I interferon (IFN) signature, but the …
Epidemiology: the current burden of tuberculosis and its determinants
R Verstraeten, M Cossa, L Martinez… - The Challenge of …, 2023 - books.google.com
Ending TB has been a global struggle for decades. Despite numerous efforts to accelerate
the reduction in incidence and mortality, TB continues to be one of the top infectious killers …
the reduction in incidence and mortality, TB continues to be one of the top infectious killers …
Distinct and overlapping immunological responses to SARS-CoV-2 and Mycobacterium tuberculosis identified by single-cell RNA-seq of co-infected whole blood
Introduction COVID-19 and tuberculosis (TB) exhibit similar symptomatic presentation and
clinical parameters. Common underlying immunological mechanisms also highlight …
clinical parameters. Common underlying immunological mechanisms also highlight …
Type III interferons are expressed in tuberculosis granulomas and can enhance anti-mycobacterial activity of macrophages
P Talukdar - 2023 - search.proquest.com
Humans and non-human primates express four subtypes of type 3 interferons (IFNλs; IFNλ1-
IFNλ4). Unlike type I interferons, which have been extensively investigated in tuberculosis …
IFNλ4). Unlike type I interferons, which have been extensively investigated in tuberculosis …
Mycobacterium tuberculosis infection associated immune perturbations correlate with antiretroviral immunity
B Tepekule, L Joerimann, CD Schenkel, L Opitz… - bioRxiv, 2023 - biorxiv.org
Infection with Mycobacterium tuberculosis (MTB) remains one of the most important
opportunistic infections in people with HIV-1 (PWH). While it is well accepted that active …
opportunistic infections in people with HIV-1 (PWH). While it is well accepted that active …
Research progress on genetic control of host susceptibility to tuberculosis.
W Hu, K Xu - Zhejiang da xue xue bao. Yi xue ban= Journal of …, 2023 - europepmc.org
Abstract “吕贝克灾难”, 双胞胎研究及收养研究等流行病学观察性研究结果都充分表明,
宿主基因是决定机体对结核分枝杆菌是否易感和感染后是否发病的重要因素 …
宿主基因是决定机体对结核分枝杆菌是否易感和感染后是否发病的重要因素 …
[PDF][PDF] Hematopoietic dysregulation caused by neutrophils underlies impaired T-cell response and enhanced susceptibility to tuberculosis.
ABSTRACT 22 Control of Mycobacterium tuberculosis (Mtb) infection requires the
generation of T cells that 23 migrate to granulomas, specialized immune structures …
generation of T cells that 23 migrate to granulomas, specialized immune structures …