DPP-4 inhibitors for treating T2DM-hype or hope? an analysis based on the current literature

K Saini, S Sharma, Y Khan - Frontiers in Molecular Biosciences, 2023 - frontiersin.org
DPP-4 inhibition is an interesting line of therapy for treating Type 2 Diabetes Mellitus (T2DM)
and is based on promoting the incretin effect. Here, the authors have presented a brief …

[HTML][HTML] Management of metabolic-associated fatty liver disease: The diabetology perspective

MS Jeeyavudeen, SKA Khan, S Fouda… - World Journal of …, 2023 - ncbi.nlm.nih.gov
The metabolic syndrome as a consequence of the obesity pandemic resulted in a
substantial increase in the prevalence of metabolic-associated fatty live disease (MAFLD) …

The blood pressure lowering effects of glucagon-like peptide-1 receptor agonists: a mini-review of the potential mechanisms

JC Ribeiro-Silva, CAM Tavares, ACC Girardi - Current opinion in …, 2023 - Elsevier
The incretin hormone glucagon-like peptide 1 (GLP-1) is a key component of the signaling
mechanisms promoting glucose homeostasis. Clinical and experimental studies …

[HTML][HTML] Lipopeptides development in cosmetics and pharmaceutical applications: a comprehensive review

M Pilz, P Cavelius, F Qoura, D Awad, T Brück - Biotechnology Advances, 2023 - Elsevier
Lipopeptides are surface active, natural products of bacteria, fungi and green-blue algae
origin, having diverse structures and functionalities. In analogy, a number of chemical …

Targeting cluster of differentiation 26/dipeptidyl peptidase 4 (CD26/DPP4) in organ fibrosis

B Ohm, I Moneke… - British Journal of …, 2023 - Wiley Online Library
Cluster of differentiation 26 (CD26)/dipeptidyl peptidase 4 (DPP4) is an exopeptidase that is
expressed as a transmembrane protein in many organs but also present in a circulating …

[HTML][HTML] Glucagon-like peptide 1 therapy: from discovery to type 2 diabetes and beyond

A Viljoen, SC Bain - Endocrinology and Metabolism, 2023 - synapse.koreamed.org
The therapeutic benefits of the incretin hormone, glucagon-like peptide 1 (GLP1), for people
with type 2 diabetes and/or obesity, are now firmly established. The evidence-base arising …

Dorothy Hodgkin lecture 2023: The enteroendocrine system—Sensors in your guts

F Reimann - Diabetic Medicine, 2023 - Wiley Online Library
Abstract Glucagon‐like peptide‐1 (GLP‐1)‐based medication is now widely employed in the
treatment of type 2 diabetes and obesity. Like other gut hormones, GLP‐1 is released from …

Identification of levomenthol derivatives as potential dipeptidyl peptidase-4 inhibitors: a comparative study with gliptins

AA Alade, SA Ahmed, S Mujwar, B Kikiowo… - Journal of …, 2023 - Taylor & Francis
Abstract Dipeptidyl peptidase-4 (DPP4) inhibitors are a potent therapeutic treatment for type
2 diabetes mellitus (T2DM). There is a family of compounds used as DPP4 inhibitors …

Glucagon-like peptide-1 is involved in the thermic effects of dietary proteins in male rodents

K Ochiai, A Muto, BS Seok, Y Doi, Y Iwasaki… - …, 2023 - academic.oup.com
Protein intake potently increases body temperature and energy expenditure, but the
underlying mechanism thereof remains incompletely understood. Simultaneously, protein …

Glucagon-like peptide 1 receptor agonists and the potential risk of pancreatic carcinoma: a pharmacovigilance study using the FDA Adverse Event Reporting System …

M Cao, C Pan, Y Tian, L Wang, Z Zhao… - International Journal of …, 2023 - Springer
Background There are increasing data on the potential risk of pancreatic carcinoma
associated with glucagon-like peptide 1 receptor agonists (GLP-1RAs). Aim The study …