Background: The American Heart Association, in conjunction with the National Institutes of
Health, annually reports the most up-to-date statistics related to heart disease, stroke, and …

The prevalence of obesity has reached pandemic proportions, and now approximately 25%
of adults in Westernized countries have obesity. Recognized as a major health concern …

Identification of individuals at highest risk of coronary artery disease (CAD)—ideally before
onset—remains an important public health need. Prior studies have developed genome …

Large-scale genome-wide association studies conducted over the last decade have
uncovered numerous genetic variants associated with cardiometabolic traits and risk factors …

Abstract Purpose of Review This review aims to examine (i) the aetiology of obesity;(ii) how
and why a perception of personal responsibility for obesity so dominantly frames this …

Obesity is the most extended metabolic alteration worldwide increasing the risk for the
development of cardiometabolic alterations such as type 2 diabetes, hypertension, and …

Polygenic risk scores (PRSs) have been among the leading advances in biomedicine in
recent years. As a proxy of genetic liability, PRSs are utilised across multiple fields and …

Cancer-associated cachexia (CAC) is a major contributor to morbidity and mortality in
individuals with non-small cell lung cancer. Key features of CAC include alterations in body …

Importance Body mass index (BMI) is an easily obtained adiposity surrogate. However, there
is variability in body composition and adipose tissue distribution between individuals with …

Genome-wide association studies (GWASs) have been mostly conducted in populations of
European ancestry, which currently limits the transferability of their findings to other …