Anti-EGFR antibodies in the management of advanced colorectal cancer

PM Kasi, MG Afable, C Herting, M Lukanowski… - The …, 2023 - academic.oup.com
Colorectal cancer is the third most common cancer worldwide, and incidence is rising in
younger individuals. Anti-EGFR antibodies, including cetuximab and panitumumab, have …

[HTML][HTML] Progress of research on molecular targeted therapies for colorectal cancer

S Huang, J Ye, X Gao, X Huang, J Huang… - Frontiers in …, 2023 - frontiersin.org
Colorectal cancer (CRC) is one of the most common malignancies, accounting for
approximately 10% of global cancer incidence and mortality. Approximately 20% of patients …

A review on emerging targeted therapies for the management of metastatic colorectal cancers

R Deshmukh, M Prajapati, RK Harwansh - Medical Oncology, 2023 - Springer
Colorectal cancers are among the most commonly found cancers over the world. In spite of
the recent advancements in diagnosis and prognosis, the management of this metastatic …

[HTML][HTML] Diagnostic accuracy of intraoperative margin assessment techniques in surgery for head and neck squamous cell carcinoma: A meta-analysis

JA Higginson, O Breik, AH Thompson, H Ashrafian… - Oral Oncology, 2023 - Elsevier
Background Positive margins following head and neck squamous cell carcinoma (HNSCC)
surgery lead to significant morbidity and mortality. Existing Intraoperative Margin …

Real-world outcomes among patients with metastatic colorectal cancer treated first line with a bevacizumab biosimilar (bevacizumab-awwb)

R Jin, AS Ogbomo, NA Accortt, LS Lal… - Therapeutic …, 2023 - journals.sagepub.com
Background: Bevacizumab-awwb (MVASI®) was the first US Food and Drug Administration-
approved biosimilar to Avastin®(reference product [RP]) for the treatment of several different …

CDX2 is a prognostic biomarker for unresectable metastatic colorectal cancer

J Mukohyama, K Agawa, K Yamashita… - Anticancer …, 2023 - ar.iiarjournals.org
Background/Aim: Colorectal cancer (CRC) with reduced expression of the homeobox
transcription factor CDX2, a master gene essential for the development and maintenance of …

[HTML][HTML] Molecular and genetic targets within metastatic colorectal cancer and associated novel treatment advancements

CG Cann, MB LaPelusa, SK Cimino, C Eng - Frontiers in Oncology, 2023 - frontiersin.org
Colorectal cancer results in the deaths of hundreds of thousands of patients worldwide each
year, with incidence expected to rise over the next two decades. In the metastatic setting …

[HTML][HTML] Targeted Therapy in the Palliative Setting of Colorectal Cancer—Survival and Medical Costs

K Inci, B Nilsson, L Ny, U Strömberg, N Wilking… - Cancers, 2023 - mdpi.com
Simple Summary Targeted therapy targeting the EGFr and vascular endothelial growth
factor (VEGF) is often combined with chemotherapy in palliative treatment of metastatic …

Epigenomic characterization of circulating tumour cells in advanced colorectal cancer

A Bao Caamaño - 2023 - minerva.usc.es
Metastatic colorectal cancer continues to be a major health burden despite advances in
detection and therapy. Molecular characterization of circulating tumour cells (CTCs), main …

Personalized and targeted therapies

M Wiśniewska, M Wiśniewski… - Physical Sciences …, 2023 - degruyter.com
Biomarker is defined as indicator of normal or pathogenic biological process or response to
an intervention or exposure. There are several categories of biomarkers but predictive …