Rare penetrant mutations confer severe risk of common diseases

PP Fiziev, J McRae, JC Ulirsch, JS Dron, T Hamp… - Science, 2023 - science.org
We examined 454,712 exomes for genes associated with a wide spectrum of complex traits
and common diseases and observed that rare, penetrant mutations in genes implicated by …

Sleep traits and risk of end-stage renal disease: a mendelian randomization study

K Li, J Zhao, W Yang, Z Ye - BMC Medical Genomics, 2023 - Springer
Background Epidemiological evidence relating sleep disorders to end-stage renal disease
(ESRD) has been obscure. The present study is sought to examine the association between …