Cefiderocol, a siderophore cephalosporin, as a treatment option for infections caused by carbapenem-resistant Enterobacterales
Carbapenem-resistant Enterobacterales (CRE) remain a significant public health threat,
and, despite recent approvals, new antibiotics are needed. Severe infections caused by …
and, despite recent approvals, new antibiotics are needed. Severe infections caused by …
Treatment of critically ill patients with cefiderocol for infections caused by multidrug-resistant pathogens: review of the evidence
P Viale, CE Sandrock, P Ramirez, GM Rossolini… - Annals of intensive …, 2023 - Springer
Appropriate antibiotic treatment for critically ill patients with serious Gram-negative infections
in the intensive care unit is crucial to minimize morbidity and mortality. Several new …
in the intensive care unit is crucial to minimize morbidity and mortality. Several new …
In vitro activity of cefiderocol against MBL-producing Gram-negative bacteria collected in North America and Europe in five consecutive annual multinational SIDERO …
M Takemura, MG Wise, MA Hackel… - Journal of …, 2023 - academic.oup.com
Objectives To evaluate the in vitro antibacterial activity of cefiderocol, a siderophore
cephalosporin against MBL-producing clinical isolates. Methods MBL-producing strains …
cephalosporin against MBL-producing clinical isolates. Methods MBL-producing strains …
An overview of Cefiderocol's therapeutic potential and underlying resistance mechanisms
Antimicrobial resistance continues to increase globally and treatment of difficult-to-treat
(DTT) infections, mostly associated with carbapenem-resistant (CR) Pseudomonas …
(DTT) infections, mostly associated with carbapenem-resistant (CR) Pseudomonas …
Cefiderocol use for the treatment of infections by carbapenem-resistant Gram-negative bacteria: An Italian multicentre real-life experience
Background Cefiderocol is a novel siderophore cephalosporin with promising activity
against most carbapenem-resistant Gram-negative bacteria (CRGNB). However, extensive …
against most carbapenem-resistant Gram-negative bacteria (CRGNB). However, extensive …
Performance evaluation of the UMIC® Cefiderocol to determine MIC in Gram-negative bacteria
L Dortet, C Niccolai, N Pfennigwerth… - Journal of …, 2023 - academic.oup.com
Background Cefiderocol is a catechol-substituted cephalosporin with potent in vitro activity
against carbapenem-resistant (CR) Gram-negative bacteria (GNB). Cefiderocol …
against carbapenem-resistant (CR) Gram-negative bacteria (GNB). Cefiderocol …
In vitro activity of cefiderocol on multiresistant bacterial strains and genomic analysis of two cefiderocol resistant strains
M Padovani, A Bertelli, S Corbellini, G Piccinelli… - Antibiotics, 2023 - mdpi.com
Cefiderocol is a new siderophore cephalosporin that is effective against multidrug-resistant
Gram-negative bacteria, including carbapenem-resistant strains. The aim of this study was to …
Gram-negative bacteria, including carbapenem-resistant strains. The aim of this study was to …
[HTML][HTML] High efficacy and enhanced synergistic activity of the novel siderophore-cephalosporin cefiderocol against multidrug-resistant and extensively drug-resistant …
L Daoud, F Al-Marzooq, A Ghazawi, F Anes… - Journal of Infection and …, 2023 - Elsevier
Background Cefiderocol (CFDC) is a novel siderophore-cephalosporin, which usually
penetrates the bacteria through the iron-uptake pathways. Data is limited on the factors …
penetrates the bacteria through the iron-uptake pathways. Data is limited on the factors …
Extreme resistance to the novel siderophore-cephalosporin cefiderocol in an extensively drug-resistant Klebsiella pneumoniae strain causing fatal pneumonia with …
L Daoud, M Allam, T Collyns, A Ghazawi… - European Journal of …, 2023 - Springer
Cefiderocol (CFDC) is the first-in-class siderophore-cephalosporin. Klebsiella pneumoniae
strain that is extremely resistant to CFDC (MIC: 256 µg/ml) was isolated for the first time in …
strain that is extremely resistant to CFDC (MIC: 256 µg/ml) was isolated for the first time in …
Infection Prevention Control Strategies of New Delhi Metallo-β-lactamase Producing Klebsiella pneumoniae
N Muresu, G Deiana, M Dettori, A Palmieri, MD Masia… - Healthcare, 2023 - mdpi.com
The spread of multi-drug resistant organisms (MDROs) is increasing at an alarming rate
worldwide. Among these, Carbapenemase-producing New Delhi Metallo-β-lactamase …
worldwide. Among these, Carbapenemase-producing New Delhi Metallo-β-lactamase …