[HTML][HTML] Human-specific genetics: new tools to explore the molecular and cellular basis of human evolution
Our ancestors acquired morphological, cognitive and metabolic modifications that enabled
humans to colonize diverse habitats, develop extraordinary technologies and reshape the …
humans to colonize diverse habitats, develop extraordinary technologies and reshape the …
Human genetic history on the Tibetan Plateau in the past 5100 years
Using genome-wide data of 89 ancient individuals dated to 5100 to 100 years before the
present (BP) from 29 sites across the Tibetan Plateau, we found plateau-specific ancestry …
present (BP) from 29 sites across the Tibetan Plateau, we found plateau-specific ancestry …
Unlocking the genome of perch–from genes to ecology and back again
Eurasian perch Perca fluviatilis has been a popular model species for decades in the fields
of aquatic ecology, community dynamics, behaviour, physiology and ecotoxicology. Yet …
of aquatic ecology, community dynamics, behaviour, physiology and ecotoxicology. Yet …
Long-term trends in human body size track regional variation in subsistence transitions and growth acceleration linked to dairying
Evidence for a reduction in stature between Mesolithic foragers and Neolithic farmers has
been interpreted as reflective of declines in health, however, our current understanding of …
been interpreted as reflective of declines in health, however, our current understanding of …
Comparing measured dietary variation within and between tropical hunter-gatherer groups to the Paleo Diet
Background Although human diets varied considerably before the spread of agriculture,
public perceptions of preagricultural diets have been strongly influenced by the Paleo Diet …
public perceptions of preagricultural diets have been strongly influenced by the Paleo Diet …
High-Altitude Andean H194R HIF2A Allele Is a Hypomorphic Allele
K Jorgensen, D Song, J Weinstein… - Molecular biology …, 2023 - academic.oup.com
Abstract For over 10,000 years, Andeans have resided at high altitude where the partial
pressure of oxygen challenges human survival. Recent studies have provided evidence for …
pressure of oxygen challenges human survival. Recent studies have provided evidence for …
[HTML][HTML] Identifying signatures of positive selection in human populations from North Africa
R Caro-Consuegra, M Lucas-Sánchez, D Comas… - Scientific Reports, 2023 - nature.com
Because of its location, North Africa (NA) has witnessed continuous demographic
movements with an impact on the genomes of present-day human populations. Genomic …
movements with an impact on the genomes of present-day human populations. Genomic …
[HTML][HTML] Human subsistence and signatures of selection on chemosensory genes
Chemosensation (olfaction, taste) is essential for detecting and assessing foods, such that
dietary shifts elicit evolutionary changes in vertebrate chemosensory genes. The transition …
dietary shifts elicit evolutionary changes in vertebrate chemosensory genes. The transition …
[PDF][PDF] Gene-by-environment interactions are pervasive among natural genetic variants
Summary Gene-by-environment (GxE) interactions, in which a genetic variant's phenotypic
effect is condition specific, are fundamental for understanding fitness landscapes and …
effect is condition specific, are fundamental for understanding fitness landscapes and …
Uncovering footprints of natural selection through spectral analysis of genomic summary statistics
Natural selection leaves a spatial pattern along the genome, with a haplotype distribution
distortion near the selected locus that fades with distance. Evaluating the spatial signal of a …
distortion near the selected locus that fades with distance. Evaluating the spatial signal of a …