The coordinating role of nuclear factor erythroid-2-related factor 2 (Nrf2) in cellular function
is undeniable. Evidence indicates that this transcription factor exerts massive regulatory …

Many pathogenic organisms need to reach either an intracellular compartment or the
cytoplasm of a target cell for their survival, replication or immune system evasion …

Leishmaniasis is a neglected disease caused by protozoa of the genus Leishmania, which
causes different clinical manifestations. Drugs currently used in the treatment such as …

Leishmaniasis is a widespread but still underdiagnosed parasitic disease that affects both
humans and animals. There are at least 20 pathogenic species of Leishmania, most of them …

(1) Background: Leishmaniasis refers to a group of anthropozoonotic diseases caused by
Leishmania. The major chemotherapeutic agent used for its treatment is Glucantime®®, but …

Production of nitric oxide (NO) by LPS-activated macrophages is due to a complex cellular
signaling initiated by TLR4 that leads to the transcription of IFN-β, which activates IRF-1 and …

Parazitičtí prvoci z rodu Leishmania během životního cyklu kolují mezi přenašeči a hostiteli,
ve kterých přicházejí do kontaktu s imunitním systémem. V těle hostitele může infekce vést k …

Background: Cutaneous leishmaniasis (CL) is a tropical parasitic infection that involves
several factors in its pathogenesis, including oxidative stress. The oxidative stress in CL may …

Leishmanioses são doenças parasitárias causadas por protozoários do gênero Leishmania
spp. Eles são transmitidos ao hospedeiro por vetores flebotomíneos infectados durante o …

INTRODUÇÃO: A leishmaniose tegumentar americana (LTA) é uma doença infecciosa não
contagiosa, causada por protozoários do gênero Leishmania. Esses parasitos intracelulares …