Evolutionary genetics and admixture in African populations

A Pfennig, LN Petersen, P Kachambwa… - Genome Biology and …, 2023 - academic.oup.com
As the ancestral homeland of our species, Africa contains elevated levels of genetic diversity
and substantial population structure. Importantly, African genomes are heterogeneous: They …

One species, many roots?

EML Scerri - Nature Ecology & Evolution, 2023 - nature.com
One species, many roots? | Nature Ecology & Evolution Skip to main content Thank you for
visiting nature.com. You are using a browser version with limited support for CSS. To obtain the …

Frequencies of pharmacogenomic alleles across biogeographic groups in a large-scale biobank

B Li, K Sangkuhl, R Whaley, M Woon, K Keat… - The American Journal of …, 2023 - cell.com
Pharmacogenomics (PGx) is an integral part of precision medicine and contributes to the
maximization of drug efficacy and reduction of adverse drug event risk. Accurate information …

[PDF][PDF] Leveraging our common African origins to understand human evolution and health

A Wonkam, A Adeyemo - Cell Genomics, 2023 - cell.com
In the March 2023 issue of Cell, Fan et al. 1 report whole-genome sequencing across 12
indigenous African populations and analyze local adaptation and evolutionary history. Here …

Insights into drivers of mobility and cultural dynamics of African hunter–gatherers over the past 120 000 years

J Zonker, C Padilla-Iglesias… - Royal Society Open …, 2023 - royalsocietypublishing.org
Humans have a unique capacity to innovate, transmit and rely on complex, cumulative
culture for survival. While an important body of work has attempted to explore the role of …

A fast, reproducible, high-throughput variant calling workflow for evolutionary, ecological, and conservation genomics

CD Mirchandani, AJ Shultz, GWC Thomas, SJ Smith… - bioRxiv, 2023 - biorxiv.org
The increasing availability of genomic resequencing datasets and high quality reference
genomes across the tree of life present exciting opportunities for comparative population …

The genomic echoes of the last Green Sahara on the Fulani and Sahelian people

E D'Atanasio, F Risi, F Ravasini, F Montinaro… - Current Biology, 2023 - cell.com
The population history of the Sahara/Sahelian belt is understudied, despite previous work
highlighting complex dynamics. 1, 2, 3, 4, 5, 6, 7 The Sahelian Fulani, ie, the largest …

Human evolution: Neanderthal footprints in African genomes

AP Ragsdale - Current Biology, 2023 - cell.com
Human and Neanderthal populations met and mixed on multiple occasions over
evolutionary time, resulting in the exchange of genetic material. New genomic analyses of …

Echoes from the last Green Sahara: whole genome analysis of Fulani, a key population to unveil the genetic evolutionary history of Africa

E D'Atanasio, F Risi, F Ravasini, F Montinaro… - bioRxiv, 2023 - biorxiv.org
Abstract Background The Sahelian Fulani are the largest nomadic pastoral ethnic group.
Their origins are still largely unknown and their Eurasian genetic component is usually …

Are we genetically literate enough for global precision health?

A Wonkam - The Lancet, 2023 - thelancet.com
Leroy Hood and Nathan Price argue with passion, excellence, and personal experience for
a proactive approach to achieving the real potential of precision health, developed around …