Over the last 17 years, there has been a remarkable increase in scientific research
concerning chronic traumatic encephalopathy (CTE). Since the publication of NINDS–NIBIB …

Alzheimer disease (AD) is the most common cause of dementia in older individuals. AD is
characterized pathologically by amyloid-β (Aβ) plaques and tau neurofibrillary tangles in the …

Alzheimer's Disease (AD) contributes to most cases of dementia. Its prominent
neuropathological features are the extracellular neuritic plaques and intercellular …

Microtubule-associated protein tau is essential for microtubule assembly and stabilization.
Hyperphosphorylation of the microtubule-associated protein tau plays an important …

Aggregates of the protein tau are proposed to drive pathogenesis in neurodegenerative
diseases. Tau can be targeted by using passively transferred antibodies (Abs), but the …

Aggregation of tau into filamentous inclusions underlies Alzheimer's disease (AD) and
numerous other neurodegenerative tauopathies. The pathogenesis of tauopathies remains …

Scientific advances over the last four decades have steadily infused the Alzheimer's disease
(AD) field with great optimism that therapies targeting Aβ, amyloid, tau, and innate immune …

Preeclampsia (PE) is the leading cause of maternal and fetal mortality globally and may
trigger dementia later in life in mothers and their offspring. However, the etiological drivers …

Traumatic brain injury (TBI) causes cognitive impairment but it remains contested regarding
which cognitive domains are most affected. Further, moderate-severe TBI is known to be …

Solid-like protein deposits found in aged and diseased human brains have revealed a
relationship between insoluble protein accumulations and the resulting deficits in neurologic …