Inflammasomes are supramolecular platforms that organize in response to various damage-
associated molecular patterns and pathogen-associated molecular patterns. Upon …

Mast cells (MCs) are tissue cells that are derived from bone marrow stem cells that
contribute to allergic reactions, inflammatory diseases, innate and adaptive immunity …

Inflammatory lung diseases represent a persistent burden for patients and the global
healthcare system. The combination of high morbidity,(partially) high mortality and limited …

The ocular tissue microenvironment is immune-privileged and uses multiple
immunosuppressive mechanisms to prevent the induction of inflammation. The retinal …

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the etiological culprit
of COronaVIrus Disease 19 (COVID-19), can enter the cells via the angiotensin-converting …

Adoptive immunotherapy expressing synthetic chimeric antigen receptors (CAR) on T cells
through in vitro modifications represents a new and innovative strategy in cancer treatment …

The intervertebral disk degeneration (IDD) and its associated conditions are an important
problem in modern medicine. The onset of IDD may be in childhood and adolescence in …

The Salmonella biofilm-associated amyloid protein, curli, is a dominant instigator of systemic
inflammation and autoimmune responses following Salmonella infection. Systemic curli …

Polycystic ovary syndrome (PCOS) is a disease with endocrine and metabolic disorders.
The main symptoms are hyperandrogenemia (HA), insulin resistance (IR), and ovulation …

Different from inflammatory arthritis, where biologicals and targeted synthetic molecules
have revolutionized the disease course, no drug has demonstrated a disease modifying …