Dry eye disease is a complex ophthalmic disorder that consists of two main subtypes,
aqueous deficient dry eye (ADDE) and evaporative dry eye disease (EDED). Due to the …

The measurement of tear film osmolarity has been suggested as a gold standard in the
diagnosis of dry eye. Many tear film physiological variables oscillate during the day. This …

Purpose: To determine the relationships of (1) tear osmolarity (TO) levels with the severity of
signs and symptoms of dry eye disease (DED) and (2) changes in TO with changes in signs …

Dry eye disease (DED) is a disorder of the ocular surface caused due to hyperosmolarity
and insufficient production of tears to moisturize the eye, which leads to less lubrication and …

Maintaining a healthy balance of tear production, preservation, and elimination is crucial for
proper eye function. Tear osmolarity and its variations have been suggested to be reliable …

Dry eye disease (DED) is an umbrella term that represents a wide spectrum of disorders with
different clinical presentations and variable risk factors. Despite significant work, the …

The focus of this thesis is tear dynamics and the regulation of tear secretion by the Lacrimal
Functional Unit (LFU), a collection of functions that control tear secretion and maintain a …