SARS-CoV-2 viral load and shedding kinetics

O Puhach, B Meyer, I Eckerle - Nature Reviews Microbiology, 2023 - nature.com
SARS-CoV-2 viral load and detection of infectious virus in the respiratory tract are the two
key parameters for estimating infectiousness. As shedding of infectious virus is required for …

Accelerating antiviral drug discovery: lessons from COVID-19

A von Delft, MD Hall, AD Kwong, LA Purcell… - Nature Reviews Drug …, 2023 - nature.com
During the coronavirus disease 2019 (COVID-19) pandemic, a wave of rapid and
collaborative drug discovery efforts took place in academia and industry, culminating in …

Infectiousness of SARS-CoV-2 breakthrough infections and reinfections during the Omicron wave

ST Tan, AT Kwan, I Rodríguez-Barraquer, BJ Singer… - Nature Medicine, 2023 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) breakthrough infections in
vaccinated individuals and reinfections in previously infected individuals have become …

Molnupiravir versus placebo in unvaccinated and vaccinated patients with early SARS-CoV-2 infection in the UK (AGILE CST-2): a randomised, placebo-controlled …

SH Khoo, R FitzGerald, G Saunders… - The Lancet Infectious …, 2023 - thelancet.com
Background The antiviral drug molnupiravir was licensed for treating at-risk patients with
COVID-19 on the basis of data from unvaccinated adults. We aimed to evaluate the safety …

Ultrasensitive lateral-flow assays via plasmonically active antibody-conjugated fluorescent nanoparticles

R Gupta, P Gupta, S Wang, A Melnykov… - Nature Biomedical …, 2023 - nature.com
Lateral-flow assays (LFAs) are rapid and inexpensive, yet they are nearly 1,000-fold less
sensitive than laboratory-based tests. Here we show that plasmonically active antibody …

Respiratory aerosols and droplets in the transmission of infectious diseases

ML Pöhlker, C Pöhlker, OO Krüger, JD Förster… - Reviews of Modern …, 2023 - APS
Knowing the physicochemical properties of exhaled droplets and aerosol particles is a
prerequisite for a detailed mechanistic understanding and effective prevention of the …

The degradation of single-use plastics and commercially viable bioplastics in the environment: A review

SN Idris, TSM Amelia, K Bhubalan, AMM Lazim… - Environmental …, 2023 - Elsevier
Plastics have become an integral part of human life. Single-use plastics (SUPs) are
disposable plastics designed to be used once then promptly discarded or recycled. This …

Viral emissions into the air and environment after SARS-CoV-2 human challenge: a phase 1, open label, first-in-human study

J Zhou, A Singanayagam, N Goonawardane… - The Lancet …, 2023 - thelancet.com
Background Effectively implementing strategies to curb SARS-CoV-2 transmission requires
understanding who is contagious and when. Although viral load on upper respiratory swabs …

Recent progress on wastewater-based epidemiology for COVID-19 surveillance: A systematic review of analytical procedures and epidemiological modeling

S Ciannella, C González-Fernández… - Science of the Total …, 2023 - Elsevier
Abstract On March 11, 2020, the World Health Organization declared the coronavirus
disease 2019 (COVID-19), whose causative agent is the Severe Acute Respiratory …

Stability and transmissibility of SARS‐CoV‐2 in the environment

Y Geng, Y Wang - Journal of Medical Virology, 2023 - Wiley Online Library
Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), the virus causing the
ongoing global coronavirus disease 2019 (COVID‐19) pandemic, is believed to be …