The metabolic activation of small-molecule drugs into electrophilic reactive metabolites is widely recognized as an indicator of idiosyncratic adverse drug reactions (IADRs). Three …
Forensic science is currently fast-growing for the development detection of the latent fingerprint. Currently, chemical dust quickly enters the body through touch or inhalation and …
Fenebrutinib is an orally available Bruton tyrosine kinase inhibitor. It is currently in multiple phase III clinical trials for the management of B-cell tumors and autoimmune disorders …
D Dalvie, AS Kalgutkar - Medicinal Chemistry Research, 2023 - Springer
A fundamental knowledge of applied organic chemistry is an important weapon in the arsenal of drug metabolism scientists, particularly ones engaged in the design and/or the …
K Nishiwaki, Y Morikawa, S Suzuki, K Shiomi… - Analytical …, 2023 - Springer
We develop a specific derivatization gas chromatography–mass spectrometry (GC–MS) method for cyanide using 1, 2, 3, 3-tetramethyl-3 H-indium iodide as the derivatization …