Antiphospholipid syndrome: advances in diagnosis, pathogenesis, and management

JS Knight, DW Branch, TL Ortel - bmj, 2023 - bmj.com
Antiphospholipid syndrome (APS) is a thrombo-inflammatory disease propelled by
circulating autoantibodies that recognize cell surface phospholipids and phospholipid …

Frequency and Clinical Significance Anti-PS/PT Antibodies in Patients with Antiphospholipid Syndrome—Single Centre Observational Study in the United Kingdom

H Noble, C Crossette-Thambiah, Z Odho… - … in Thrombosis and …, 2023 - thieme-connect.com
Antiphospholipid syndrome (APS) is an acquired autoimmune disease defined by the
presence of persistently positive antiphospholipid antibodies (aPLs) on two or more …

Antiphospholipid antibody positivity in early systemic lupus erythematosus is associated with subsequent vascular events

N Farina, R Abdulsalam, T McDonnell… - …, 2023 - academic.oup.com
Objective aPL are found in the blood of 20–30% of patients with SLE. Although aPL cause
vascular thrombosis in the antiphospholipid syndrome, it is not clear whether positive aPL …

Laboratory testing for non-criteria antiphospholipid antibodies: antibodies toward the domain I of beta2-glycoprotein I (aDI)

KMJ Devreese - Hemostasis and Thrombosis: Methods and Protocols, 2023 - Springer
Anti-β2GPI antibodies (aβ2GPI) are one of the laboratory criteria for antiphospholipid
syndrome (APS), along with lupus anticoagulant (LA) and anticardiolipin antibodies (aCL). A …

Antiphospholipid antibody-mediated NK cell cytotoxicity

G Manukyan, E Kriegova, L Slavik, Z Mikulkova… - Journal of Reproductive …, 2023 - Elsevier
Antiphospholipid syndrome (APS) is an autoimmune thrombophilia that is characterised by
thrombosis and obstetric complications in the presence of antiphospholipid antibodies …

Thrombotic risk assessment in antiphospholipid syndrome: do noncriteria antibodies contribute?

Ö Uludağ, S Çinar, T McDonnell… - Turkish Journal of …, 2023 - journals.tubitak.gov.tr
Background/aim: In this cross-sectional study, it was aimed to test the predictive value of
noncriteria antiphospholipid antibodies (aPL) in addition to the global antiphospholipid …

An Antiphospholipid Antibody Profile as a Biomarker for Thrombophilia in Systemic Lupus Erythematosus

R Hisada, T Atsumi - Biomolecules, 2023 - mdpi.com
Despite recent advances in treatment and significant improvements in prognosis, thrombosis
remains the major cause of death in systemic lupus erythematosus (SLE). Antiphospholipid …

Protection of β2GPI Deficient Mice from Thrombosis Reflects a Defect in PAR3-facilitated Platelet Activation

PP Kulkarni, RK Alluri, M Godwin, GL Forbes… - bioRxiv, 2023 - biorxiv.org
Background Antibodies to β2-glycoprotein I (β2GPI) cause thrombosis in antiphospholipid
syndrome, however the role of β2GPI itself in regulation of coagulation pathways in vivo is …

Utilidad de biomarcadores no incluidos en los criterios de clasificación para la identificación y seguimiento de pacientes con Síndrome Antifosfolipídico

L Naranjo Rondán - 2023 - docta.ucm.es
Utilidad de biomarcadores no incluidos en los criterios de clasificación para la identificación y
seguimiento de pacientes con Page 1 UNIVERSIDAD COMPLUTENSE DE MADRID FACULTAD …

Methods: A multicenter, cross-sectional and observational study was conducted on 303 patients recruited from six European hospitals who

D Alves, F Tedesco, PR Ames, M Serrano… - Recent advances in …, 2023 - books.google.com
Background: Antiphospholipid syndrome (APS) is a multisystemic autoimmune disorder
characterized by thrombotic events and/or gestational morbidity in patients with …