Current rates of purchasing of antibiotics without a prescription across sub-Saharan Africa; rationale and potential programmes to reduce inappropriate dispensing …

TM Sono, E Yeika, A Cook, A Kalungia… - Expert review of anti …, 2023 - Taylor & Francis
Introduction Antimicrobial resistance (AMR) is a global concern. Currently, the greatest
mortality due to AMR is in Africa. A key driver continues to be high levels of dispensing of …

A narrative review of antibiotic prescribing practices in primary care settings in South Africa and potential ways forward to reduce antimicrobial resistance

A Chigome, N Ramdas, P Skosana, A Cook… - Antibiotics, 2023 - mdpi.com
There are concerns with the current prescribing of antibiotics in both the private and public
primary care settings in South Africa. These concerns need to be addressed going forward …

[HTML][HTML] Need for effective detection and early warnings for epidemic and pandemic preparedness planning in the context of multi-hazards: lessons from the COVID-19 …

T Kamalrathne, D Amaratunga, R Haigh… - International Journal of …, 2023 - Elsevier
The need for effective early detection and timely surveillance for a robust pandemic and
epidemic early warning and preparedness has been widely discussed amidst the Covid-19 …

Breast cancer management in the era of Covid-19; key issues, contemporary strategies, and future implications

AHMSU Prodhan, DZ Islam, SS Khandker… - … Cancer: Targets and …, 2023 - Taylor & Francis
During the COVID-19 pandemic, several priority diseases were not getting sufficient
attention. Whilst breast cancer is a fatal disease affecting millions worldwide, identification …

Antibiotic utilization patterns for different wound types among surgical patients: findings and implications

Z Saleem, U Ahsan, A Haseeb, U Altaf, N Batool… - Antibiotics, 2023 - mdpi.com
Antimicrobial prophylaxis is effective in reducing the rate of surgical site infections (SSIs)
post-operatively. However, there are concerns with the extent of prophylaxis post …

Ongoing strategies to improve antimicrobial utilization in hospitals across the Middle East and North Africa (MENA): Findings and implications

A Haseeb, Z Saleem, AF Maqadmi, RA Allehyani… - Antibiotics, 2023 - mdpi.com
Antimicrobial resistance (AMR) is an increasing global concern, increasing costs, morbidity,
and mortality. National action plans (NAPs) to minimize AMR are one of several global and …

Effects of nirmatrelvir/ritonavir on midazolam and dabigatran pharmacokinetics in healthy participants

DS Cox, M Rehman, T Khan, K Ginman… - British Journal of …, 2023 - Wiley Online Library
Aims To evaluate pharmacokinetics (PK) and safety after coadministration of
nirmatrelvir/ritonavir or ritonavir alone with midazolam (a cytochrome P450 3A4 substrate) …

A narrative review of recent antibiotic prescribing practices in ambulatory care in Tanzania: findings and implications

A Massele, AM Rogers, D Gabriel, A Mayanda… - Medicina, 2023 - mdpi.com
Background and objectives: There are concerns with the current prescribing practices of
antibiotics in ambulatory care in Tanzania, including both the public and private sectors …

COVID-19 vaccine uptake and associated factors among adolescents and youths: Findings and implications for future vaccination programmes

S Mudenda, JC Meyer, JO Fadare… - PLOS Global Public …, 2023 - journals.plos.org
Adolescents and youths are a key part of the population that needs to be protected against
the coronavirus disease 2019 (COVID-19). This is because they are more likely to spread …

Effects of itraconazole and carbamazepine on the pharmacokinetics of nirmatrelvir/ritonavir in healthy adults

DS Cox, L Van Eyck, S Pawlak… - British Journal of …, 2023 - Wiley Online Library
Aims The objective of this study was to evaluate the effects of a strong cytochrome P450
family (CYP) 3A4 inhibitor (itraconazole) and inducer (carbamazepine) on the …