Advances in the carbonic anhydrase (CA, EC 4.2. 1.1) research over the last three decades
are presented, with an emphasis on the deciphering of the activation mechanism, the …

This review summarizes recent evidence on how mid‐life hypertension,
hyperhomocysteinemia (HHcy) and blood pressure variability, as well as late‐life …

Boron-containing compounds (BCC) exert effects on neurons. After the expanding of both
the identification and synthesis of new BCC, novel effects in living systems have been …

Numerous physiological and pathological cellular processes depend on the ability to detect
and respond to changes in gas levels both inside and outside the cell [1]. Overall, the ability …

Acanthamoeba castellanii is an amoeba that inhabits soil and water in every part of the
world. Acanthamoeba infection of the eye causes keratitis and can lead to a loss of vision …

Introduction Cerebrovascular pathology is an early and causal hallmark of Alzheimer's
disease (AD), in need of effective therapies. Methods Based on the success of our previous …

Amyloid beta (Aβ) deposition within the brain vasculature is an early hallmark of Alzheimer's
disease (AD), which triggers loss of brain vascular smooth muscle cells (BVSMCs) in …

Metallothioneins (MT) are regulators of the metals Zn (II) and Cu (I) and act as antioxidants
in many organisms, including in humans. Isoform 3 (MT3) is expressed constitutively in …

In a previous study, in silico screening of the binding of almost all proteins in the Protein
Data Bank to each of the five noble gases xenon, krypton, argon, neon, and helium was …

Teleosts comprise half of all vertebrates and have successfully invaded every aquatic
habitat on Earth. They owe this success, at least in part, to their unique oxygenation system …