Comprehensive clinical assays for molecular diagnostics of gliomas: the current state and future prospects

A Penkova, O Kuziakova, V Gulaia, V Tiasto… - Frontiers in Molecular …, 2023 - frontiersin.org
Glioma is one of the most intractable types of cancer, due to delayed diagnosis at advanced
stages. The clinical symptoms of glioma are unclear and due to a variety of glioma subtypes …

Complete chloroplast genome of Lens lamottei reveals intraspecies variation among with Lens culinaris

S Kurt, Y Kaymaz, D Ateş, MB Tanyolaç - Scientific Reports, 2023 - nature.com
Lens lamottei is a member of the Fabaceae family and the second gene pool of the genus
Lens. The environmental factors that drove the divergence among wild and cultivated …

miR-383-5p, miR-181a-5p, and miR-181b-5p as predictors of response to first-generation somatostatin receptor ligands in acromegaly

DG Henriques, RL Miranda, RS Dezonne… - International Journal of …, 2023 - mdpi.com
Acromegaly is a chronic systemic disease caused in the vast majority of cases by growth
hormone (GH)-secreting adenoma, with surgery being the first-line treatment. When a cure is …

Characteristics of the fecal microbiome of piglets with diarrhea identified using shotgun metagenomics sequencing

M Gryaznova, Y Smirnova, I Burakova, P Morozova… - Animals, 2023 - mdpi.com
Simple Summary Diarrhea in newborn piglets is one of the important problems for the
agricultural industry. It is believed that this disease is associated with changes in the …

Trypanosoma cruzi dysregulates expression profile of piRNAs in primary human cardiac fibroblasts during early infection phase

KJ Rayford, A Cooley, AW Strode, I Osi… - Frontiers in Cellular …, 2023 - frontiersin.org
Trypanosoma cruzi, the etiological agent of Chagas Disease, causes severe morbidity,
mortality, and economic burden worldwide. Though originally endemic to Central and South …

Cross-platform comparisons for targeted bisulfite sequencing of MGISEQ-2000 and NovaSeq6000

J Sun, M Su, J Ma, M Xu, C Ma, W Li, R Liu, Q He… - Clinical …, 2023 - Springer
Background An accurate and reproducible next-generation sequencing platform is essential
to identify malignancy-related abnormal DNA methylation changes and translate them into …

Global analysis in nonobstructive Azoospermic testis identifies miRNAs critical to spermatogenesis

F Piryaei, H Mozdarani, MA Sadighi Gilani… - Andrologia, 2023 - Wiley Online Library
Introduction. The etiology of male infertility characterized by non‐obstructive azoospermia is
largely unknown, especially at the molecular level. Identifying dysregulated microRNAs …

Transcriptomic analysis of Amaranthus retroflex resistant to PPO-inhibitory herbicides

Y Guo, Y Wang, X Zang, C Luo, C Huang, K Cong… - Plos one, 2023 - journals.plos.org
Amaranthus retroflexus L. is one of the malignant weeds which can cause a reduction in the
soybean yield. We found a population of A. retroflexus (RQ) resistant to fomesafen through …

Adaptation and Experimental Validation of Clinical RNA Sequencing Protocol Oncobox for MGI DNBSEQ-G50 Platform

NR Khilal, MV Suntsova, DI Knyazev… - … ), Supplement Series B …, 2023 - Springer
RNA sequencing (RNAseq) is currently a method of choice for the high-throughput RNA-
level analysis of gene expression. Furthermore, RNAseq data can be used for the prediction …

Next-Generation Sequencing for Companion Diagnostics and Precision Medicine

IJ Kim, P Mendez, D Jablons - Advances in Medical Imaging …, 2023 - taylorfrancis.com
The tremendous recent advances in genetic studies owe a great deal to the completion of
human genome project in 2003 and the availability of next-generation sequencing (NGS) …