Development and challenges of synthetic retinoid formulations in cancer

S Assi, H El Hajj, B Hayar, C Pisano… - Current Drug …, 2023 - ingentaconnect.com
Retinoids represent a class of chemical compounds derived from or structurally and
functionally related to vitamin A. Retinoids play crucial roles in regulating a range of crucial …

Novel 2-substituted-quinoxaline analogs with potential antiproliferative activity against breast cancer: insights into cell cycle arrest, topoisomerase II, and EGFR activity

MG Salem, SAA El-Ata, EH Elsayed, SN Mali… - RSC …, 2023 - pubs.rsc.org
Breast cancer is a global health concern, with increasing disease burden and disparities in
access to healthcare. Late diagnosis and limited treatment options in underserved areas …

The Antitumor Effect of the DNA Polymerase Alpha Inhibitor ST1926 in Glioblastoma: A Proteomics Approach

C El-Baba, Z Ayache, M Goli, B Hayar… - International Journal of …, 2023 - mdpi.com
Glioblastoma Multiforme (GBM) is the most aggressive form of malignant brain tumor. The
median survival rate does not exceed two years, indicating an imminent need to develop …