Social health factors (eg, social activities or social support) and cognitive activity
engagement have been associated with dementia risk, but their neural substrates have not …

Increasing evidence suggests that intact social bonds are protective against age-related
morbidity, while bond disruption and social isolation increase the risk for multiple age …

Background: Social isolation has been suggested to increase the risk to develop cognitive
decline. However, our knowledge on causality and neurobiological underpinnings is still …

Social concepts such as loneliness and social isolation are fairly new factors that have been
recently gaining attention as to their involvement in changes in cognitive function and …

Loneliness is associated with differences in resting-state functional connectivity (RSFC)
within and between large-scale networks in early-and middle-aged adult cohorts. However …

As a social and public health concern, loneliness is associated with an abundance of
negative life outcomes such as depressive symptomatology, mortality, and sleep …

Objectives: Olfaction is an important correlate of later-life health, including cognition and
mortality risk. Environmental enrichment protects against olfactory decline, yet little research …

The anterior cingulate cortex (ACC) and right ventrolateral prefrontal cortex (VLPFC) are
thought to have important roles in loneliness (feeling of social isolation/exclusion) …

Introduction As social animals, our health depends in part on interactions with other human
beings. Yet millions suffer from chronic social isolation, including those in nursing/assisted …

In aging populations, increasing amounts of older adults are reporting high levels of
loneliness. Previous research has demonstrated that people reporting more loneliness have …