Cancer is one of the most fatal diseases of recent times that causes several deaths every
year. The disease variations in different parts of the world, the impact of available medical …

The potential of chiral metal–organic frameworks (MOFs) for circularly polarized (CP) optics
has been largely unexplored. Herein, we have successfully deposited monolithic and highly …

This mini‐review summarizes catalytic asymmetric synthetic methodologies for preparing 2,
5‐diketopiperazine (DKP) frameworks since 1990, with two types of synthetic precursor …

Understanding the mechanisms of mycotoxin toxicity is crucial for establishing effective
guidelines and preventive strategies. In this study, machine learning models based on …

The tetrazole moiety is a versatile scaffold in medicinal chemistry due to its specific structure
and essential roles in biosciences. Here, a supramolecular behavior of newly synthesized …

Chemotherapy is one of the most important treatment modalities for liver cancer, especially
for those who are judged as being unsuitable for surgical resection, local ablative therapy, or …

We report a novel approach to access spirocyclic compounds containing a diketopiperazine
(DKP) motif fused on a pyrrolidine ring. The shared spirocyclic carbon is at the ketone …

In our ongoing quest to design effective antimicrobial peptides (AMPs), this study aimed to
elucidate the mechanisms governing cyclic amphiphilic AMPs and their interactions with …

Cyclic dipeptides with two intramolecular peptide bonds forming a six-membered 2, 5-
diketopiperazine ring are gaining significant attention due to their biological and chemical …

Cyclic dipeptides (CDPs) are small, highly bioactive peptides produced by plants, animals,
and fungi. They consist of two cyclized amino acids forming a four-carbon central …