Defending against SARS-CoV-2: The T cell perspective
P Almendro-Vázquez, R Laguna-Goya… - Frontiers in …, 2023 - frontiersin.org
SARS-CoV-2-specific T cell response has been proven essential for viral clearance, COVID-
19 outcome and long-term memory. Impaired early T cell-driven immunity leads to a severe …
19 outcome and long-term memory. Impaired early T cell-driven immunity leads to a severe …
Hybrid immunity to SARS-CoV-2 from infection and vaccination—evidence synthesis and implications for new COVID-19 vaccines
JR Spinardi, A Srivastava - Biomedicines, 2023 - mdpi.com
COVID-19 has taken a severe toll on the global population through infections,
hospitalizations, and deaths. Elucidating SARS-CoV-2 infection-derived immunity has led to …
hospitalizations, and deaths. Elucidating SARS-CoV-2 infection-derived immunity has led to …
Additive effects of booster mRNA vaccination and SARS-CoV-2 Omicron infection on T cell immunity across immunocompromised states
Suboptimal immunity to SARS-CoV-2 mRNA vaccination has frequently been observed in
individuals with various immunodeficiencies. Given the increased antibody evasion …
individuals with various immunodeficiencies. Given the increased antibody evasion …
Adaptive immune responses to SARS-CoV-2 persist in the pharyngeal lymphoid tissue of children
Most studies of adaptive immunity to SARS-CoV-2 infection focus on peripheral blood, which
may not fully reflect immune responses at the site of infection. Using samples from 110 …
may not fully reflect immune responses at the site of infection. Using samples from 110 …
[HTML][HTML] Major alterations to monocyte and dendritic cell subsets lasting more than 6 months after hospitalization for COVID-19
Introduction After more than two years the Coronavirus disease-19 (COVID-19) pandemic
continues to burden healthcare systems and economies worldwide, and it is evident that the …
continues to burden healthcare systems and economies worldwide, and it is evident that the …
Role of T cells in severe COVID-19 disease, protection, and long term immunity
JM Hermens, C Kesmir - Immunogenetics, 2023 - Springer
Infection with SARS-CoV-2 causes wide range of disease severities from asymptomatic to
life-threatening disease. Understanding the contribution of immunological traits in immunity …
life-threatening disease. Understanding the contribution of immunological traits in immunity …
Limited induction of polyfunctional lung-resident memory T cells against SARS-CoV-2 by mRNA vaccination compared to infection
DKJ Pieren, SG Kuguel, J Rosado, AG Robles… - Nature …, 2023 - nature.com
Resident memory T cells (TRM) present at the respiratory tract may be essential to enhance
early SARS-CoV-2 viral clearance, thus limiting viral infection and disease. While long-term …
early SARS-CoV-2 viral clearance, thus limiting viral infection and disease. While long-term …
[HTML][HTML] T cell immune memory after covid-19 and vaccination
The T cell memory response is a crucial component of adaptive immunity responsible for
limiting or preventing viral reinfection. T cell memory after infection with the SARS-CoV-2 …
limiting or preventing viral reinfection. T cell memory after infection with the SARS-CoV-2 …
Dissecting the Protective Effect of CD8+ T Cells in Response to SARS-CoV-2 mRNA Vaccination and the Potential Link with Lymph Node CD8+ T Cells
M Chen, V Venturi, CML Munier - Biology, 2023 - mdpi.com
Simple Summary Coronavirus disease 2019 (COVID-19) is a respiratory disease caused by
the novel coronavirus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …
the novel coronavirus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …
Machine learning identifies T cell receptor repertoire signatures associated with COVID-19 severity
T cell receptor (TCR) repertoires are critical for antiviral immunity. Determining the TCR
repertoire composition, diversity, and dynamics and how they change during viral infection …
repertoire composition, diversity, and dynamics and how they change during viral infection …