Non-mutational neoantigens in disease

LJ Stern, C Clement, L Galluzzi, L Santambrogio - Nature immunology, 2024 - nature.com
The ability of mammals to mount adaptive immune responses culminating with the
establishment of immunological memory is predicated on the ability of the mature T cell …

Anti-MDA5 antibody-positive dermatomyositis: pathogenesis and clinical progress

X Lu, Q Peng, G Wang - Nature Reviews Rheumatology, 2024 - nature.com
Anti-melanoma differentiation-associated protein 5 (MDA5) antibody-positive
dermatomyositis (MDA5-DM) is a subtype of dermatomyositis. Although the aetiology and …

Integrated longitudinal multiomics study identifies immune programs associated with acute COVID-19 severity and mortality

JP Gygi, C Maguire, RK Patel, P Shinde… - The Journal of …, 2024 - Am Soc Clin Investig
BACKGROUND Patients hospitalized for COVID-19 exhibit diverse clinical outcomes, with
outcomes for some individuals diverging over time even though their initial disease severity …

COVID-19 in patients with anemia and haematological malignancies: risk factors, clinical guidelines, and emerging therapeutic approaches

S Kakavandi, B Hajikhani, P Azizi, F Aziziyan… - Cell Communication and …, 2024 - Springer
Extensive research in countries with high sociodemographic indices (SDIs) to date has
shown that coronavirus disease 2019 (COVID-19) may be directly associated with more …

Increased risk of thyroid eye disease following Covid-19 vaccination

I Muller, D Consonni, E Crivicich… - The Journal of …, 2024 - academic.oup.com
Context SARS-CoV-2 infection and Covid-19 vaccines have been associated with thyroid
disorders. Objective We analyzed the risk of thyroid eye disease (TED) following Covid-19 …

Type 1 diabetes: A new vision of the disease based on endotypes

CS Weston, BO Boehm, P Pozzilli - … /Metabolism Research and …, 2024 - Wiley Online Library
Diagnosis and management of type 1 diabetes (T1D) have remained largely unchanged for
the last several years. The management of the disease remains primarily focused on its …

Pathophysiological, immunological, and inflammatory features of long COVID

K Bohmwald, B Diethelm-Varela… - Frontiers in …, 2024 - frontiersin.org
The COVID-19 pandemic continues to cause severe global disruption, resulting in significant
excess mortality, overwhelming healthcare systems, and imposing substantial social and …

Precision nutrition to reset virus-induced human metabolic reprogramming and dysregulation (HMRD) in long-COVID

AS Naidu, CK Wang, P Rao, F Mancini… - npj Science of …, 2024 - nature.com
Abstract SARS‐CoV‐2, the etiological agent of COVID-19, is devoid of any metabolic
capacity; therefore, it is critical for the viral pathogen to hijack host cellular metabolic …

Guillain–Barré syndrome: immunopathogenesis and therapeutic targets

S Liu, WW Zhang, L Jia, HL Zhang - Expert Opinion on Therapeutic …, 2024 - Taylor & Francis
ABSTRACT Introduction Guillain–Barré syndrome (GBS) is a group of acute immune-
mediated disorders in the peripheral nervous system. Both infectious and noninfectious …

Self-DNA driven inflammation in COVID-19 and after mRNA-based vaccination: lessons for non-COVID-19 pathologies

M Heil - Frontiers in Immunology, 2024 - frontiersin.org
The coronavirus disease 2019 (COVID-19) pandemic triggered an unprecedented
concentration of economic and research efforts to generate knowledge at unequalled speed …