Functions of mucosal associated invariant T cells in eye diseases
C Fukui, S Yamana, Y Xue, M Shirane… - Frontiers in …, 2024 - frontiersin.org
Mucosal-associated invariant T (MAIT) cells are a unique subset of T cells that recognizes
metabolites derived from the vitamin B2 biosynthetic pathway. Since the identification of …
metabolites derived from the vitamin B2 biosynthetic pathway. Since the identification of …
Ankylosing spondylitis: acute/subacute vs. chronic iridocyclitis-a bidirectional two-sample Mendelian randomization study
H Li, Y Xu, Q Guo, T Zhang, S Zhou, M Wu… - Frontiers in …, 2024 - frontiersin.org
Background Observational studies found associations between ankylosing spondylitis (AS)
and iridocyclitis (IC), but the causality remained unconfirmed. Methods We employed two …
and iridocyclitis (IC), but the causality remained unconfirmed. Methods We employed two …
Genetic variations of IL10 and IL6R genes in acute anterior uveitis in Han Chinese
L Li, F Li, J Shan, K Xie, P Zhou, H Zhu, X Jin, L Du… - BMC …, 2024 - Springer
Background Several autoimmune disorders have been linked to polymorphisms in IL10 and
IL6R genes. This research aimed to study whether single nucleotide polymorphisms (SNPs) …
IL6R genes. This research aimed to study whether single nucleotide polymorphisms (SNPs) …
Low uveitis rates in patients with axial spondyloarthritis treated with bimekizumab: pooled results from phase 2b/3 trials
MA Brown, M Rudwaleit, FA Van Gaalen… - Annals of the …, 2024 - ard.bmj.com
Objectives Acute anterior uveitis ('uveitis') is a common axial spondyloarthritis (axSpA)
extramusculoskeletal manifestation. Interleukin (IL)-17 is implicated in its pathogenesis …
extramusculoskeletal manifestation. Interleukin (IL)-17 is implicated in its pathogenesis …
Genome-wide association study of anterior uveitis
F Koskimaki, O Ahokas, FinnGen… - medRxiv, 2024 - medrxiv.org
Importance: Anterior uveitis is an intraocular disease characterized by inflammation of the
iris and the ciliary body and known to co-occur with autoimmune diseases. This is the largest …
iris and the ciliary body and known to co-occur with autoimmune diseases. This is the largest …
Correlation of TBX21 gene polymorphisms with ankylosing spondylitis in a Chinese population
L Li, J Shan, H Fang, G An, M Zhang… - International Journal …, 2024 - Wiley Online Library
Genome‐wide association studies analysis has revealed associations between ankylosing
spondylitis (AS) and loci on the TBX21 gene across various populations. This study aimed to …
spondylitis (AS) and loci on the TBX21 gene across various populations. This study aimed to …
[PDF][PDF] IL-17+ CD8+(Tc17) T cells and Tissue Resident Memory (TRM) cells in Spondyloarthritis
CD Hughes - kclpure.kcl.ac.uk
IL-17A is a proinflammatory cytokine that plays a role in the pathogenesis of several
autoimmune conditions including psoriasis, psoriatic arthritis (PsA), axial spondyloarthritis …
autoimmune conditions including psoriasis, psoriatic arthritis (PsA), axial spondyloarthritis …